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08-06-2024 | Arterial Occlusive Disease | Review

Coronary Microvascular Dysfunction in Women

Authors: Scott M. Gaignard, Esha K. Dave, Rachel K. Warnock, Kristina S. Bortfeld, Valeria M. Moncayo, Puja K. Mehta

Published in: Current Cardiovascular Risk Reports

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Abstract  

Purpose of Review

Patients who are suspected of having symptoms from myocardial ischemia routinely undergo coronary angiography to evaluate for obstructive coronary artery disease (CAD). However, a substantial proportion of patients with ischemia are found to have no obstructive coronary arteries (INOCA), a condition that is associated with major adverse cardiovascular events and recurrent angina hospitalizations.

Recent Findings

Epicardial coronary vascular dysfunction and coronary microvascular dysfunction (CMD) are prevalent in a majority of INOCA patients. CMD is prognostic in both men and women, although women have more angina and lower quality of life with this condition. CMD can be detected by non-invasive stress testing modalities, but coronary angiography with coronary function testing provides a comprehensive evaluation of vascular abnormalities in the diagnoses of CMD.

Summary

Treatment of this challenging condition requires a tailored approach that includes targeting lifestyle, addressing risk factors, and use of anti-anginal strategies to manage symptoms and improve quality of life. This mini review highlights the diagnosis and management of CMD, a condition that is often underappreciated and underrecognized.
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Metadata
Title
Coronary Microvascular Dysfunction in Women
Authors
Scott M. Gaignard
Esha K. Dave
Rachel K. Warnock
Kristina S. Bortfeld
Valeria M. Moncayo
Puja K. Mehta
Publication date
08-06-2024
Publisher
Springer US
Published in
Current Cardiovascular Risk Reports
Print ISSN: 1932-9520
Electronic ISSN: 1932-9563
DOI
https://doi.org/10.1007/s12170-024-00738-5
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