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Current Neurology and Neuroscience Reports

Apraxia: From Neuroanatomical Pathways to Clinical Manifestations

  • Open Access
  • 16-11-2024
  • Apraxia
  • Review
Published in:
Authors
Sarah Stoll
Lukas Lorentz
Ferdinand Binkofski
Jennifer Randerath
Published in
Current Neurology and Neuroscience Reports | Issue 1/2025

Abstract

Purpose of Review

Apraxia typically involves impairments in gesture production and tool use, affecting daily life activities. This article reviews current conceptualizations and developments in diagnostic and therapy.

Recent Findings

Apraxia has been studied in various neurological conditions, particularly stroke and dementia, but recent studies show gesturing deficits in psychiatric populations as well. Promising results have emerged from integrative treatment approaches involving intensive practice of gestures or daily activities. However, several reviews have noted the only marginal progress in apraxia therapy research despite new technologies, like virtual reality and brain stimulation, offering fresh opportunities for assessment and therapy.

Summary

Advances in lesion-symptom mapping and connectivity analyses led to more detailed neuroanatomical models emphasizing parallel and gradual processing. These models facilitate the understanding of underlying mechanisms of motor cognitive performance and its decline. Finally, the digital era prompts the need to study digital tool use in apraxia, with initial efforts underway.
Title
Apraxia: From Neuroanatomical Pathways to Clinical Manifestations
Authors
Sarah Stoll
Lukas Lorentz
Ferdinand Binkofski
Jennifer Randerath
Publication date
16-11-2024
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Image Credits
Close-up of a woman's hands/© Ratirath / stock.adobe.com (symbolic image with model), Human brain illustration/© (M) CHRISTOPH BURGSTEDT / SCIENCE PHOTO LIBRARY / Getty Images, Navigating neuroimaging in Alzheimer’s care: Practical applications and strategies for integration/© Springer Health+ IME