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Journal of Assisted Reproduction and Genetics

Open Access 06-11-2024 | Anxiety | Assisted Reproduction Technologies

Impact of perceived social support on anxiety and depression in women undergoing in vitro fertilization-embryo transfer: the role of psychological resilience

Authors: Yuying Yan, Ya Ma, Lidan Xu, Yuehong Lv

Published in: Journal of Assisted Reproduction and Genetics

Abstract

Purpose

This study aimed to analyze the current status of women’s perception of social support levels, psychological resilience, anxiety, and depression levels during IVF-ET, as well as investigate the influence of perceived social support and psychological resilience on the anxiety and depression levels of women undergoing IVF-ET and the mediating role of psychological resilience in this process.

Methods

In this study, a convenience sampling method was used to administer a questionnaire survey among 433 women undergoing IVF-ET. Then, multivariate linear regression models were applied to identify factors influencing anxiety and depression. Lastly, mediation effect analysis was conducted to explore the mediating role of psychological resilience.

Results

The incidence of anxiety and depression was 42% and 46.4%, respectively. The mean score of the Perceived Social Support Scale (PSSS) indicated a high to moderate level of support, while the mean score of the Conner-Davidson Resilience Scale (CD-RISC) suggested moderate psychological resilience. Perceived social support was positively correlated with psychological resilience, and both were negatively correlated with anxiety and depression. Perceived social support and psychological resilience were identified as influencing factors of anxiety and depression (P < 0.001). Moreover, there was a partial mediating effect of psychological resilience between perceived social support and both anxiety and depression (P < 0.01).

Conclusions

These results highlight the need for healthcare providers to assess patients’ levels of psychological resilience and perceived social support when developing mental health interventions in order to mitigate the risk of anxiety and depression and concomitantly enhance fertility outcomes.

Koochaksaraei FY, Simbar M, Khoshnoodifar M, Faramarzi M, Nasiri M. Interventions promoting mental health dimensions in infertile women: a systematic review. BMC Psychol. 2023;11:254. https://doi.org/10.1186/s40359-023-01285-1.CrossRefPubMedPubMedCentral

Abulizi M, Xu H, Abuduguli A, Zhao W, He L, Zhang C. Dual mediating effects of social support and fertility stress on mindfulness and fertility quality of life in infertile men: a case-control study. Front Psychol. 2023;14:1138282. https://doi.org/10.3389/fpsyg.2023.1138282.CrossRefPubMedPubMedCentral

Liu Y, Deng Y, Liu L, Shen J, Zhang L, Wang X. A Study on the relationship between fertility pressure, perceived partner responsive-ness and family resilience in female infertility patients and their spouses. J Nurs Sci. 2024;39:1–5.

Ying LY, Wu LH, Loke AY. Gender differences in experiences with and adjustments to infertility: a literature review. Int J Nurs Stud. 2015;52:1640–52. https://doi.org/10.1016/j.ijnurstu.2015.05.004.CrossRefPubMed

Zhou Y, Sun Z, Song J. Research progress on the impact of anxiety and depression on embryo transfer outcomes of in vitro fertilization. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2023;52:61–7. https://doi.org/10.3724/zdxbyxb-2022-0473.CrossRefPubMed

Wang L, Tang Y, Wang Y. Predictors and incidence of depression and anxiety in women undergoing infertility treatment: a cross-sectional study. PLoS ONE. 2023;18:e0284414. https://doi.org/10.1371/journal.pone.0284414.CrossRefPubMedPubMedCentral

Zhang F, Zhu S, Deng P. Evaluation of Perceived Social Support Scale used in study of social support among hospitalized patients in China. Chin Nurs Res. 2018;32:2048–52. https://doi.org/10.12102/j.issn.1009-6493.2018.13.015.CrossRef

Jamilian H, Jamilian M, Soltany S. The comparison of quality of life and social support among fertile and infertile women. J Patient Saf Qual Improv. 2017;5:521–5.

Liu Y, Zhu J, Zhao J, Tian Y. Relationships of family function and social support with mental health of infertile women. Chinese Journal of Women and Child Health Research. 2022;33(5):14–9. https://doi.org/10.3969/j.issn.1673-5293.2022.05.003.CrossRef

10.

Lei A, You H, Luo B, Ren J. The associations between infertility-related stress, family adaptability and family cohesion in infertile couples. Sci Rep. 2021;11:24220. https://doi.org/10.1038/s41598-021-03715-9.CrossRefPubMedPubMedCentral

11.

Zhang X, Deng X, Mo Y, Li Y, Song X, Li H. Relationship between infertility-related stress and resilience with posttraumatic growth in infertile couples: gender differences and dyadic interaction. Hum Reprod. 2021;36:1862–70. https://doi.org/10.1093/humrep/deab096.CrossRefPubMed

12.

Huang Y, Wu R, Wu J, Yang Q, Zheng S, Wu K. Psychological resilience, self-acceptance, perceived social support and their associations with mental health of incarcerated offenders in China. Asian J Psychiatr. 2020;52:102166. https://doi.org/10.1016/j.ajp.2020.102166.CrossRefPubMed

13.

Li Y, Zhang X, Shi M, Guo S, Wang L. Resilience acts as a moderator in the relationship between infertility-related stress and fertility quality of life among women with infertility: a cross-sectional study. Health Qual Life Outcomes. 2019;17(1):38. https://doi.org/10.1186/s12955-019-1099-8.CrossRefPubMedPubMedCentral

14.

Zimet GD, Powell SS, Farley GK, Werkman S, Berkoff KA. Psychometric characteristics of the multidimensional scale of perceived social support. J Pers Assess. 1990;55:610–7. https://doi.org/10.1080/00223891.1990.9674095.CrossRefPubMed

15.

Jiang QJ. Perceived social support scale. Chin J Behav Med Sci. 2001;10(10):41–3.

16.

Connor KM, Davidson JR. Development of a new resilience scale: the Connor-Davidson Resilience Scale (CD-RISC). Depress Anxiety. 2003;18:76–82. https://doi.org/10.1002/da.10113.CrossRefPubMed

17.

Spitzer RL, Kroenke K, Williams JB, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166:1092–7. https://doi.org/10.1001/archinte.166.10.1092.CrossRefPubMed

18.

Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16:606–13. https://doi.org/10.1046/j.1525-1497.2001.016009606.x.CrossRefPubMedPubMedCentral

19.

Hayes AF. PROCESS: a versatile computational tool for observed variable mediation, moderation, and conditional process modeling. Behav Res Methods. 2012;6.

20.

Ong HL, Vaingankar JA, Abdin E, Sambasivam R, Fauziana R, Tan ME, Chong SA, Goveas RR, Chiam PC, Subramaniam M. Resilience and burden in caregivers of older adults: moderating and mediating effects of perceived social support. BMC Psychiatry. 2018;18:27. https://doi.org/10.1186/s12888-018-1616-z.CrossRefPubMedPubMedCentral

21.

Zhang J, Yin Y, Wang A, Li H, Li J, Yang S, Wu Y, Zhang J. Resilience in patients with lung cancer: structural equation modeling. Cancer Nurs. 2021;44:465–72. https://doi.org/10.1097/ncc.0000000000000838.CrossRefPubMed

22.

Pei M, Xie L, Liu H, Ma X, Li S, Hu J. Status quo of distress disclosure among infertile patients and its influencing factors. Nurs J Chin People’s Lib Army. 2022;39:9–12.

23.

Ayed N, Toner S, Priebe S. Conceptualizing resilience in adult mental health literature: a systematic review and narrative synthesis. Psychol Psychother. 2019;92:299–341. https://doi.org/10.1111/papt.12185.CrossRefPubMed

24.

Wang DH, Zhao Q, Liao J, Guo JB, Shao J, Hu JP. Effect of psychological resilience and perceived social support on post-traumatic growth in patients undergoing IVF-ET. J Reprod Med. 2021;30:1445–9.

25.

Campbell-Sills L, Stein MB. Psychometric analysis and refinement of the Connor-Davidson Resilience Scale (CD-RISC): validation of a 10-item measure of resilience. J Trauma Stress. 2007;20:1019–28. https://doi.org/10.1002/jts.20271.CrossRefPubMed

26.

Xu X, Wang S, Pan X. Relationship between anxiety emotions and personality traits of primary caregivers of senile dementia patients: mediating effect of psychological resilience. China J Health Psychol. 2024;32:1141–6.

27.

Konstantopoulou G, Iliou T, Karaivazoglou K, Iconomou G, Assimakopoulos K, Alexopoulos P. Associations between (sub) clinical stress- and anxiety symptoms in mentally healthy individuals and in major depression: a cross-sectional clinical study. BMC Psychiatry. 2020;20:428. https://doi.org/10.1186/s12888-020-02836-1.CrossRefPubMedPubMedCentral

28.

Zhao Q. The relationship between negative life events and depression of senior high school students: the moderation of resilience and educational intervention. Chengdu University; 2024. p 22.

29.

Maroufizadeh S, Hosseini M, Foroushani AR, Omani-Samani R, Amini P. Application of the dyadic data analysis in behavioral medicine research: marital satisfaction and anxiety in infertile couples. BMC Med Res Methodol. 2018;18:117. https://doi.org/10.1186/s12874-018-0582-y.CrossRefPubMedPubMedCentral

30.

Ju Q, Xu L. Clinical curative effect of hysteroscopy-laparoscopy combined with supportive psychotherapy in the treatment of oviduct obstructive infertility and the influence onanxiety, depression, coping style and quality of life. China J Health Psychol. 2019;27:523–7.

31.

Hu M. Analysis of related factors of depression and anxiety in female infertility patients. Qingdao University; 2018. p 18.

32.

Al-Jadiri A, Tybor DJ, Mulé C, Sakai C. Factors associated with resilience in families of children with autism spectrum disorder. J Dev Behav Pediatr. 2021;42:16–22. https://doi.org/10.1097/dbp.0000000000000867.CrossRefPubMed

33.

Ma D, Bai C, Mao X, Cao F. Relation of emotion regulation strategies to depression and anxiety symptoms in infertile patients. Chin Ment Health J. 2023;37:662–71.

34.

Wang W, Yang F, Bai Y, Lu Y, Mao X. Association between domain-specific physical activity and mental health status after embryo transfer in IVF-ET-assisted pregnancy patients. Sci Rep. 2024;14:4928. https://doi.org/10.1038/s41598-024-55097-3.CrossRefPubMedPubMedCentral

35.

Yin Y, Lyu M, Chen Y, Zhang J, Li H, Li H, Xia G, Zhang J. Self-efficacy and positive coping mediate the relationship between social support and resilience in patients undergoing lung cancer treatment: a cross-sectional study. Front Psychol. 2022;13:953491. https://doi.org/10.3389/fpsyg.2022.953491.CrossRefPubMedPubMedCentral

36.

Sun Z, Lai L. Effect of social support on health-promoting behavior of floating elderly people-the mediating role of self-efficacy. Soft Sci Health. 2023;37:37–42.

37.

Dai K, Li R, Zheng L, Li Y, Li D, Wang W. Evaluation of factors associated with the anxiety and depression of infertility patients and the effect on in vitro fertilization outcomes. Chin J Reprod Contracept. 2018;18(7). https://doi.org/10.3760/cma.j.issn.2096-2916.2018.07.010.

38.

Carvalho IG, Bertolli ED, Paiva L, Rossi LA, Dantas RA, Pompeo DA. Anxiety, depression, resilience and self-esteem in individuals with cardiovascular diseases. Rev Lat Am Enfermagem. 2016;24:e2836. https://doi.org/10.1590/1518-8345.1405.2836.CrossRefPubMedPubMedCentral

39.

Zhang X. The relationship between fertility stress, social support and depressive symptoms in female infertility patients: the mediating role of psychological resilience. China Medical University; 2020. p 26.

40.

Ristevska-Dimitrovska G, Filov I, Rajchanovska D, Stefanovski P, Dejanova B. Resilience and quality of life in breast cancer patients. Open Access Maced J Med Sci. 2015;3:727–31. https://doi.org/10.3889/oamjms.2015.128.CrossRefPubMedPubMedCentral

Title: Impact of perceived social support on anxiety and depression in women undergoing in vitro fertilization-embryo transfer: the role of psychological resilience
Authors: Yuying Yan
Ya Ma
Lidan Xu
Yuehong Lv
Publication date: 06-11-2024
Publisher: Springer US
Keywords: Anxiety
Infertility
Infertility
In Vitro Fertilization
In Vitro Fertilisation
Published in: Journal of Assisted Reproduction and Genetics
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-024-03308-1

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