Skip to main content
Top

22-09-2023 | Anticoagulant | Response to Letter to the Editor

Reply: Comparison of Two Anticoagulants for Pain Associated with Platelet-Rich Plasma Injections

Authors: Ertuğrul Karanfil, Ali Doğan, Metin Görgü

Published in: Aesthetic Plastic Surgery

Login to get access

Abstract

We read the letter titled "Comparison of Two Anticoagulants for Pain Associated with Platelet-Rich Plasma Injections" authored by Pensato et al. in Aesthetic Plastic Surgery. The authors emphasized an important point. PRP treatments have a lot of variables; preparation method, application, amount of PRP injections, and content (such as number of platelet concentration, presence of leucocytes, and pH). However, in our study, we focused on the pain of injections. We showed that there is a pain difference by using different anticoagulants during PRP preparation, but we did not investigate for possible reason of this pain difference. The use of different anticoagulants may have caused changes in the content, and these alterations could be responsible for the variation in pain. Researches could be done to investigate the reason and the physiology of this effect.
Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.​springer.​com/​00266.
Literature
5.
go back to reference Russell RP, Apostolakos J, Hirose T et al (2013) Variability of platelet-rich plasma preparations. Sports Med Arthrosc Rev 21:186–190CrossRefPubMed Russell RP, Apostolakos J, Hirose T et al (2013) Variability of platelet-rich plasma preparations. Sports Med Arthrosc Rev 21:186–190CrossRefPubMed
6.
go back to reference Franco D, Franco T, Schettino AM et al (2012) Protocol for obtaining platelet-rich plasma (PRP), platelet-poor plasma (PPP), and thrombin for autologous use. Aesthet Plast Surg 36:1254–1259CrossRef Franco D, Franco T, Schettino AM et al (2012) Protocol for obtaining platelet-rich plasma (PRP), platelet-poor plasma (PPP), and thrombin for autologous use. Aesthet Plast Surg 36:1254–1259CrossRef
7.
go back to reference Araki J, Jona M, Eto H et al (2012) Optimized preparation method of platelet-concentrated plasma and noncoagulating platelet-derived factor concentrates: maximization of platelet concentration and removal of fibrinogen. Tissue Eng Part C Methods 18:176–185CrossRefPubMed Araki J, Jona M, Eto H et al (2012) Optimized preparation method of platelet-concentrated plasma and noncoagulating platelet-derived factor concentrates: maximization of platelet concentration and removal of fibrinogen. Tissue Eng Part C Methods 18:176–185CrossRefPubMed
Metadata
Title
Reply: Comparison of Two Anticoagulants for Pain Associated with Platelet-Rich Plasma Injections
Authors
Ertuğrul Karanfil
Ali Doğan
Metin Görgü
Publication date
22-09-2023
Publisher
Springer US
Published in
Aesthetic Plastic Surgery
Print ISSN: 0364-216X
Electronic ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-023-03652-0