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Annals of Intensive Care

Issue 1/2025

Content (193 Articles)

Guyton’s hemodynamic mosaic: crafting fluid management with precision

  • Open Access
  • Letter to the Editor

Rogerio Da Hora Passos, Luciano Ribeiro Pereira Silva, Leonardo Van De Wiel Barros Urbano Andari, Uri Adrian Prync Flato, Murillo Santucci Cesar Assunção, Thiago Domingos Corrêa

The prognostic role of cardiac and inflammatory biomarkers in extubation failure in patients with COVID-19 acute respiratory distress syndrome

Carline N. L. Groenland, Adinde H. Siemers, Eric A. Dubois, Diederik Gommers, Leo Heunks, Evert-Jan Wils, Vivan J. M. Baggen, Henrik Endeman

Estimated prevalence of post-intensive care cognitive impairment at short-term and long-term follow-ups: a proportional meta-analysis of observational studies

Mu-Hsing Ho, Yi-Wei Lee, Lizhen Wang

Evaluating the effects of continuous veno-venous hemodiafiltration on O2 and CO2 removal and energy expenditure measurement using indirect calorimetry

Weronika Wasyluk, Robert Fiut, Marcin Czop, Agnieszka Zwolak, Wojciech Dąbrowski, Manu L N G Malbrain, Joop Jonckheer

Comparison of the efficacy and safety of Landiolol and Esmolol in critically ill patients: a propensity score-matched study

Xiang Si, Hao Yuan, Rui Shi, Wenliang Song, Jiayan Guo, Jinlong Jiang, Tao Yang, Xiaoxun Ma, Huiming Wang, Minying Chen, Jianfeng Wu, Xiangdong Guan, Xavier Monnet

Time-varying intensity of ventilatory inefficiency and mortality in patients with acute respiratory distress syndrome

Lianlian Jiang, Hui Chen, Wei Chang, Qin Sun, Xueyan Yuan, Zongsheng Wu, Jianfeng Xie, Ling Liu, Yi Yang

Why do we use transpulmonary thermodilution and pulmonary artery catheter in severe shock patients?

  • Open Access
  • Shock
  • Editorial

Xavier Monnet, Christopher Lai, Daniel De Backer

Procedural sedative effect of remimazolam in ICU patients on invasive mechanical ventilation: a randomised, prospective study

Youli Tian, Jintong Li, Minggen Jin, YiHua Piao, Jisheng Sheng, Zhixiong Mei, Qingsong Cui, Lilin Li

Critically ill adult patients with acute leukemia: a systematic review and meta-analysis

Dara Chean, David Luque-Paz, Daniele Poole, Sofiane Fodil, Etienne Lengliné, Thibault Dupont, Achille Kouatchet, Michael Darmon, Élie Azoulay

Renin–angiotensin–aldosterone system activation in plasma as marker for prognosis in critically ill patients with COVID-19: a prospective exploratory study

Katharina Krenn, Felix Kraft, Luana Mandroiu, Verena Tretter, Roman Reindl-Schwaighofer, Theresa Clement, Oliver Domenig, Matthias G. Vossen, Gregor Riemann, Marko Poglitsch, Roman Ullrich

Personalized neuron-specific enolase level based on EEG pattern for prediction of poor outcome after cardiac arrest

Juliette Pelle, Estelle Pruvost-Robieux, Florence Dumas, Antonin Ginguay, Julien Charpentier, Clara Vigneron, Frédéric Pène, Jean Paul Mira, Alain Cariou, Sarah Benghanem

Biomarkers of sepsis-induced coagulopathy: diagnostic insights and potential therapeutic implications

Anaïs Curtiaud, Toshiaki Iba, Eduardo Angles-Cano, Ferhat Meziani, Julie Helms

Impact of frailty and older age on weaning from invasive ventilation: a secondary analysis of the WEAN SAFE study

  • Open Access
  • Research

Caoimhe M. Laffey, Rionach Sheerin, Omid Khazaei, Bairbre A. McNicholas, Tài Pham, Leo Heunks, Giacomo Bellani, Laurent Brochard, Dana Tomescu, Andrew J. Simpkin, John G. Laffey

Psychological symptoms, quality of life and dyadic relations in family members of intensive care survivors: a multicentre, prospective longitudinal cohort study

Sumeet Rai, Dale M. Needham, Rhonda Brown, Teresa Neeman, Krishnaswamy Sundararajan, Arvind Rajamani, Rakshit Panwar, Mary Nourse, Frank M. P. van Haren, Imogen Mitchell

Formal guidelines from an expert panel: intensive care unit medical staffing, organisation and working hours to improve quality of life at work in France

Nicolas Terzi, Guillaume Thiery, Nicolas Bèle, Naike Bigé, David Brossier, Alexandre Boyer, Edouard Couty, Laëtitia Flender, Cyril Manzon, Jean-Paul Mira, Sofia Ortuno, Vincent Peigne, Marie-Cécile Poncet, Sylvain Renolleau, Jean-Philippe Rigaud, Bérengère Vivet, Khaldoun Kuteifan

Correction: Identification and validation of respiratory subphenotypes in patients with COVID-19 acute respiratory distress syndrome undergoing prone position

Monica R. da Cruz, Pedro Azambuja, Katia S. C. Torres, Fernanda Lima‑Setta, Andre M. Japiassu, Denise M. Medeiros

Impact of mechanical ventilation on severe acute kidney injury in critically ill patients with and without COVID-19 – a multicentre propensity matched analysis

Fabian Perschinka, Timo Mayerhöfer, Teresa Engelbrecht, Alexandra Graf, Paul Zajic, Philipp Metnitz, Michael Joannidis

Extremely early initiation of vasopressors might not decrease short-term mortality for adults with septic shock: a systematic review and meta-analysis

Cheng-Hsin Ma, Jack Healy, Ebrima Kinteh, Cheng-Chin Ma, Ching-Fang Tiffany Tzeng, Eric H. Chou, Chin-Chieh Wu, Shih-Chieh Shao, Kuan-Fu Chen

The role of viscoelastic tests in the diagnosis of sepsis-induced coagulopathy (SIC)

Toshiaki Iba, Julie Helms, Jerrold H. Levy

Oxygenation improvement and duration of prone positioning are associated with ICU mortality in mechanically ventilated COVID-19 patients

Silvia De Rosa, Nicolò Sella, Giacomo Bellani, Giuseppe Foti, Andrea Cortegiani, Giulia Lorenzoni, Dario Gregori, Annalisa Boscolo, Lucia Cattin, Muhammed Elhadi, Giorgio Fullin, Eugenio Garofalo, Leonardo Gottin, Alberto Grassetto, Salvatore Maurizio Maggiore, Elena Momesso, Mario Peta, Daniele Poole, Roberto Rona, Ivo Tiberio, Andrea Zanoletti, Emanuele Rezoagli, Paolo Navalesi, Marco Abastanotti, Mohamed Abdel-Maboud Abdel-Maboud, Abdelfatah Abdellateef Abdelmageed, Eissa Abdullah, Ahmed Mohammed Abodina, Aymen Abuelyamen, Abdurraouf Abusalama, Tareg Abdalla Abuzaid, Romina Aceto, Stefano Addesa, Daniela Alampi, Amer Aldhalia, Risoli Alessio, Maytham Al-juaifari, Raja Ahmed Alqandouz, Mohammed Al-Sadawi, Marco Anderloni, Cannone Andrea, Enrico Andriolo, Botto Anna, Benvenuto Antonini, Gian Marco Anzellotti, Matteo Aritzu, Ahmed K. Awad, Flavio Badii, Hibah Bileid Bakeer, Aziza Bakri, Andrea Ballin, Massimo Barattini, Mattia Barotti, Mara Bassi, Mattia Bellandi, Marzia Bellin, Agrippino Bellissima, Annalisa Benini, Francesco Berruto, Giacomo Berta, Marco Berti, Emanuela Biagioni, Eugenio Biamonte, Giacomo Bianchetti, Andrea Bianchin, Manuela Biasetto, Muhannud Binnawara, Maria Bisi, Maria Maddalena Bitondo, Nicoletta Boffa, Michela Bombino, Benedetta Bonazzi, Elisa Bonetta, Elisa Boni, Sara Borga, Vincenzo Bosco, Gloria Boscolo, Veronica Bozzon, Luca Brazzi, Alessandro Bristot, Niccolò Brumana, Andrea Bruni, Chiara Bruscagnin, Stefano Busani, Guido Bussone, Pietro Caironi, Tiffany Calocero, Matteo Campagnolo, Claudine Canepa, Riccardo Carlon, Alfonso Carrara, Antonio Castelli, Giulia Catalisano, Martina Cavinato, Francesca Ceccaroni, Maurizio Cecconi, Martina Cedrone, Marcello Ceola Graziadei, Matteo Cesana, Nicola Cilloni, Enrico Colombo, Riccardo Colombo, Irene Coloretti, Sabrina Congedi, Angela Corea, Nicola Cornacchia, Silvia Corrado, Valentina Cricca, Chiara Crivellari, Wanda Cursio, Ernesto Dalla Mora, Lorenzo Dall’Ara, Vinicio Danzi, Luca Davicco, Alessandro De Cassai, Alessandro Devigili, Salvatore Di Blasi, Antonino Di Fede, Antonia Di Giannantonio, Pierluigi Di Giannatale, Luna Di Matteo, Giovanni Di Noto, Luca Di Tizio, Katia Donadello, Chiara Donatelli, Deyaa Elden Elbakheet, Gallo Elisa, Moataz Maher Emara, Haneen Esaadi, Mirca Fabbris, Massimo Ferluga, Luigi Ferrante, Francesco Filippone, Francesco Filippone, Elena Finotto, Ilaria Fior, Edoardo Forin, Tommaso Fossali, Rosa Fracchia, Salvo Francesco, Alessandra Gioia Francesconi, Nicola Franchetti, Sara Frisella, Regina Frontera, Roberto Fumagalli, Elisa Furlani, Lorenzo Gamberini, Elisa Gamberini, Emiliano Gamberini, Leonardo Gandolfi, Bernardetta Ganzerla, Silvia Gasperi, Ilenia Gatto, Federico Geraldini, Monica Geremia, Marco Giani, Massimo Girardis, Lorenzo Giuntoli, Ilaria Godi, Gianlorenzo Golino, Beatrice Gottardi, Antonio Grande, Massimiliano Greco, Daniela Guerra, Amedeo Guzzardella, Abdurrahman Haddud, Hashim Talib Hashim, Aliae A. R. Mohamed Hussein, Blangetti Ilaria, Teresa Iob, Giovanni Carmine Iovino, Mariachiara Ippolito, Stefano Isgrò, Cristina Jovinelli, Abdulmuhaymin Khalleefah, Ali Abdulnasir Kredan, Riccardo La Rosa, Claudio La Spisa, Luca Landolfi, Thomas Langer, Annalisa Lerose, Federico Linassi, Jacopo Lion, Giulia Lo Scrudato, Antonella Lombardo, Federico Longhini, Marta Lubian, Giulia Luccarelli, Alberto Lucchini, Aurora Magliocca, Giorgio Maiorelli, Ilaria Mariani, Anna Marinello, Francesco Marrazzo, Marina Alessandra Martin, Nicolo Martinetti, Ettore Martinez, Alvise Martini, Marilena Matteo, James Mattson, Jessica Giuseppina Maugeri, Federica Mazzanti, Francesca Medici, Luca Melchior, Lorenza Menato, Beatrice Milan, Maiseloon Mogahed, Francesco Mojoli, Silvia Mongodi, Jonathan Montomoli, Giorgia Montrucchio, Lorenza Moretto, Giuseppe Moschini, Elena Munari, Giuseppe Neri, Rosella Nicoletti, Alice Nova, Nicoletta Nuzzo, Andrea Maria Olivieri, Sara Olivieri, Sebastiano Ongaro, Anita Orlando, Eman Othman, Davide Ottolina, Michele Pagani, Giacomo Paluzzano, Giulio Panciera, Valesano Paolo, Francesco Papaccio, Marcella Parente, Zoe Parimisi, Laura Pasin, Lucia Alessandra Pasqua, Federica Pavan, Matteo Perona, Paolo Persona, Tommaso Pettenuzzo, Angelo Pezzi, Elisa Pistollato, Enrico Polati, Melissa Polo Fritz, Gilda Ponzone, Matteo Pozzi, Antonella Prandini, Nicoletta Predonzani, Chiara Premoli, Davide Raimondi Cominesi, Jacopo Rama, Linda Ramahi, Ginevra Randon, Marta Repishti, Andrea Restivo, Mara Ricci, Veronica Rizzello, Erika Roat, Monica Rocco, Andrea Rodi, Egle Rondelli, Vincenzo Russotto, Debora Saggioro, Francesco Saglietti, Abdurraouf Said, Gabriele Sales, Abdulhamid Ahmed Saliga, Reem Salih, Michele Salvagno, Antonio Massimo Sammarco, Jacopo Santi, Carola Santi, Elisabetta Saraceni, Gaetano Scaramuzzo, Chiara Schiavolin, Valerio Schinetti, Vittorio Schweiger, Elena Serafini, Teodora Serana, Luca Serano, Laila Esnoussi Shalabi, Haitam Shames, Salvatore Simari, Caterina Simoni, Simone Smiraglia, Fabio Soccorsi, Alessandra Soragni, Silvana Sorrentino, Savino Spadaro, Stefano Spina, Marta Talamonti, Francesco Talarico, Chiara Natalia Tartivita, Tommaso Tenaglia, Francesco Terranova, Denise Testini, Fabio Toffoletto, Anna Toniolo, Morena Tonzar, Giulia Torsello, Tommaso Travaglini, Fabrizio Tritapepe, Luigi Tritapepe, Letizia Troisi, Fabrizio Turvani, Lucrezia Urso, Rita Vaia Liouras, Paolo Valente, Maria Sole Vallecoccia, Paola Vergano, Sara Vergine, Luigi Vetrugno, Vanessa Zambelli, Mostafa Zanaty, Francesco Zarantonello, Michela Zardin, Francesca Zini, Eugenia Zoppellaro

Correction: Fluid accumulation syndrome in sepsis and septic shock: pathophysiology, relevance and treatment—a comprehensive review

Carmen Andrea Pfortmueller, Wojciech Dabrowski, Rob Wise, Niels van Regenmortel, Manu L. N. G. Malbrain

Effect of early and later prone positioning on outcomes in invasively ventilated COVID-19 patients with acute respiratory distress syndrome: analysis of the prospective COVID-19 critical care consortium cohort study

Andrew J. Simpkin, Bairbre A. McNicholas, David Hannon, Robert Bartlett, Davide Chiumello, Heidi J. Dalton, Kristen Gibbons, Nicole White, Laura Merson, Eddy Fan, Mauro Panigada, Giacomo Grasselli, Anna Motos, Antoni Torres, Ferran Barbé, Pauline Yeung Ng, Jonathon P. Fanning, Alistair Nichol, Jacky Y. Suen, Gianluigi Li Bassi, John F. Fraser, John G. Laffey

Sepsis-induced coagulopathy (SIC) in the management of sepsis

Yun Ji

[18F]FDG PET/CT identifies infectious and inflammatory foci in persistent critical illness

  • Open Access
  • Research

Bram van Leer, Jelle L. G. Haitsma Mulier, Cornelis P. van Stee, Kiki M. Demenaga, Riemer H. J. A. Slart, Matijs van Meurs, Andor W. J. M. Glaudemans, Maarten W. N. Nijsten, Lennie P. G. Derde, Janesh Pillay

Thrombocytopenia in the intensive care unit: diagnosis and management

Frédéric Pène, Lene Russell, Cécile Aubron

AI for the hemodynamic assessment of critically ill and surgical patients: focus on clinical applications

Frederic Michard, Marijn P. Mulder, Filipe Gonzalez, Filippo Sanfilippo

Mechanical power is not associated with mortality in COVID-19 mechanically ventilated patients

Enric Barbeta, Cláudia Barreiros, Edoardo Forin, Amedeo Guzzardella, Anna Motos, Laia Fernández-Barat, Albert Gabarrús, Adrián Ceccato, Ricard Ferrer, Jordi Riera, Oscar Peñuelas, José Ángel Lorente, David de Gonzalo-Calvo, Jessica Gonzalez, Rosario Amaya-Villar, José Manuel Añón, Ana Balan, Carme Barberà, José Barberán, Aaron Blandino, Maria Victoria Boado, Elena Bustamante-Munguira, Jesús Caballero, María Luisa Cantón-Bulnes, Cristina Carbajales, Nieves Carbonell, Mercedes Catalán-González, Nieves Franco, Cristóbal Galbán, Víctor D. Gumucio-Sanguino, Maria Del Carmen de la Torre, Emilio Díaz, Ángel Estella, Elena Gallego, José Manuel Gómez, Arturo Huerta, Ruth Noemí Jorge García, Ana Loza-Vázquez, Judith Marin-Corral, María Cruz Martin Delgado, Amalia Martínez, Ignacio Martínez, Juan Lopez, Guillermo M. Albaiceta, María Teresa Nieto, Mariana Andrea Novo, Yhivian Peñasco, Felipe Pérez-García, Pilar Ricart, Alejandro Rodríguez, Victor Sagredo, Angel Sánchez-Miralles, Susana Sancho, Ferran Roche-Campo, Lorenzo Socias, Jordi Solé-Violan, Luis Tamayo, José Trenado, Alejandro Úbeda, Luis Jorge Valdivia, Pablo Vidal, Ferran Barbé, Jordi Vallverdú, Antoni Torres, Berta Adell-Serrano, Alexander Agrifoglio, María Aguilar Cabello, Luciano Aguilera, Victoria Alcaraz-Serrano, Cesar Aldecoa, Cynthia Alegre, Sergio Álvarez, Antonjo Álvarez Ruiz, Rut Andrea, José Ángel, Marta Arrieta, J. Ignacio Ayestarán, Joan Ramon Badia, Mariona Badía, Orville Báez Pravia, Begoña Balsera, Laura Barbena, Tommaso Bardi, Patricia Barral Segade, Marta Barroso, José Ángel Berezo García, Judit Bigas, Rafael Blancas, María Luisa Blasco Cortés, María Boado, María Bodi Saera, Neus Bofill, María Teresa Bouza Vieiro, Leticia Bueno, Juan Bustamante-Munguira, Lucia Cachafeiro, David Campi Hermoso, Sandra Campos Fernández, Iosune Cano, Maria Luisa Cantón-Bulnes, Pablo Cardina Fernández, Laura Carrión García, Sula Carvalho, Núria Casacuberta-Barberà, Manuel Castellà, Andrea Castellví, Pedro Castro, Ramon Cicuendez Ávila, Catia Cillóniz, Luisa Clar, Cristina Climent, Jordi Codina, Pamela Conde, Sofía Contreras, María Cruz Martin, Raul de Pablo Sánchez, Diego De Mendoza, Cecilia del Busto Martínez, Yolanda Díaz, María Digna Rivas Vilas, Cristina Dólera Moreno, Irene Dot, Pedro Enríquez Giraudo, Inés Esmorís Arijón, Teresa Farre Monjo, Javier Fernández, Carlos Ferrando, Albert Figueras, Eva Forcadell-Ferreres, Lorena Forcelledo Espina, Àngels Furro, Felipe García, Beatriz García, Emilio García Prieto, Carlos García Redruello, Amaia García Sagastume, Maria Luisa Gascón Castillo, Gemma Gomà, Vanesa Gómez Casal, Silvia Gómez, Carmen Gómez Gonzalez, Jessica González, Federico Gordo, Maria Pilar Gracia, Alba Herraiz, Rubén Herrán-Monge, Mercedes Ibarz, Silvia Iglesias, Maria Teresa Janer, Gabriel Jiménez, Mar Juan Díaz, Karsa Kiarostami, Juan I. Lazo Álvarez, Miguel León, Alexandre López-Gavín, Ana López Lago, Desire Macias Guerrero, Nuria Mamolar Herrera, Rafael Mañez Mendiluce, Cecilia L Mantellini, Gregorio Marco Naya, Pilar Marcos, Enrique Marmol Peis, Paula Martín Vicente, María Martínez, Carmen Eulalia Martínez Fernández, Maria Dolores Martínez Juan, Juan Fernando Masa Jimenez, Joan Ramon Masclans, Emilio Maseda, Eva María Menor Fernández, Mar Miralbés, Josman Monclou, Juan Carlos Montejo-González, Neus Montserrat, María Mora Aznar, Pedro Moral-Parras, Dulce Morales, Sara Guadalupe Moreno Cano, David Mosquera Rodríguez, Rosana Muñoz-Bermúdez, José María Nicolás, Ramon Nogue Bou, Rafaela Nogueras Salinas, Marta Ocón, Ana Ortega, Sergio Ossa, Pablo Pagliarani, Anna Parera Pous, Francisco Parrilla, Leire Pérez Bastida, Purificación Pérez, Gloria Pérez Planelles, Eva Pérez Rubio, David Pestaña Laguna, Àngels Piñol-Tena, Javier Prados, Andrés Pujol, Núria Ramon Coll, Gloria Renedo Sanchez-Giron, Laura Rodriguez, Felipe Rodríguez de Castro, Silvia Rodríguez, Covadonga Rodríguez Ruiz, Jorge Rubio, Alberto Rubio López, Miriam Ruiz Miralles, Pablo Ryan Murúa, Eva Saborido Paz, Ana Salazar Degracia, Miguel Sanchez, Ana Sánchez, Bitor Santacoloma, Maria Teresa Sariñena, Marta Segura Pensado, Lidia Serra, Mireia Serra-Fortuny, Ainhoa Serrano Lázaro, Lluís Servià, Laura Soliva, Carla Speziale, Daniel Tognetti, Adrián Tormos, Mateu Torres, Sandra Trefler, Javier Trujillano, Luis Urrelo-Cerrón, Estela Val, Luis Valdivia Ruiz, Montse Vallverdú, Maria Van der Hofstadt Martin-Montalvo, Sabela Vara Adrio, Nil Vázquez, Javier Vengoechea, Pablo Vidal Cortes, Clara Vilà-Vilardel, Judit Vilanova, Tatiana Villada Warrington, Hua Yang, Minlan Yang, Ana Zapatero, Júlia Vidal

The trajectory of sleep after critical illness: a 24-month follow-up study

Mario Henríquez-Beltrán, Iván D. Benítez, Rafaela Vaca, Sally Santisteve, Maria Aguilà, Anna Vila, Olga Minguez, Carlos Rodríguez-Muñoz, Anna Galán-González, Sulamita Carvalho-Brugger, Paula González, Paula Rodríguez, Jesús Caballero, Carme Barberà, Gerard Torres, Gonzalo Labarca, Mar Malla-Banyeres, Anna Moncusí-Moix, Antoni Torres, David de Gonzalo-Calvo, Ferran Barbé, Jessica González, Adriano D. S. Targa

End-of-life decision disparities according to the gross national income in critically ill patients: a secondary analysis of the ETHICUS-2 study

  • Open Access
  • Research

Ignacio Martin-Loeches, Charles L. Sprung, Eric Wolsztynski, Rachael Cusack, Suzana Margareth Lobo, Alessandro Protti, Alexander Avidan

High-dose intravenous vitamin C reduce C-reactive protein levels, fluid retention, and APACHE II scores in patients with moderately severe acute pancreatitis: a prospective, randomized, double-blinded, placebo-controlled study

Bing Zhao, Wenwu Sun, Yihui Wang, Li Ma, Menglu Gui, Jiaoyan Li, Xianxian Yu, Xing Qi, Ning Ning, Silei Sun, Mengjiao Li, Yi Yao, Tongtian Ni, Juan He, Zhitao Yang, Ying Chen, Huiqiu Sheng, Meihua Shen, Jian Li, Jun Huang, Enqiang Mao

Triggers of viral encephalitis: a brain teaser to be solved!

Romain Sonneville, Annie Lannuzel, Cyrille Mathieu, Daniel Gonzalez-Dunia, Raphael Gaudin

Optimising fluid therapy during venoarterial extracorporeal membrane oxygenation: current evidence and future directions

  • Open Access
  • ECMO
  • Review

Ali Jendoubi, Quentin de Roux, Solène Ribot, Victor Desauge, Tom Betbeder, Lucile Picard, Bijan Ghaleh, Renaud Tissier, Matthias Kohlhauer, Nicolas Mongardon

Severe hemoptysis associated with lung cancer in the ICU: recurrence and outcome

Raphael Salvayre, Clément Hanotin, Antoine Parrot, Julien Dessajan, Alexandre Elabbadi, Nicolas Pasquier-Meunier, Muriel Fartoukh, Matthias Barral, Aude Gibelin

Relative faecal abundance to predict extended-spectrum β-lactamase-producing Enterobacterales related ventilator‑associated pneumonia

Pierre Bay, Paul-Louis Woerther, Vincent Fihman, Ségolène Gendreau, Pascale Labedade, Antoine Gaillet, Florian Jolly, Guillaume Carteaux, Nicolas de Prost, Jean-Winoc Decousser, Armand Mekontso-Dessap, Keyvan Razazi

Which carbon footprint for my ICU? Benchmark, hot spots and perspectives

  • Open Access
  • Research

Pierre Bardoult, Elodie Cadic, Olivier Brichory, Véronique Marie, Caroline Rouxel, Christophe Millet, Magalie Daudin, Elodie Peguet, Nicolas Massart

Characteristics and outcomes of ECMO cannula-related infections: a European multicenter retrospective study

  • Open Access
  • ECMO
  • Research

Sofia Ortuno, Nicolas Massart, Charles Vidal, Etienne de Montmollin, Adrien Bouglé, Nicolas Nesseler, Frank Bidar, Benjamin Assouline, Paul Masi, Samuel Henri, Sami Hraiech, Hadrien Rozé, Francesca Manicone, Charles-Edouard Luyt

Management of severe acute encephalopathy in the ICU: an expert consensus statement from the french society of intensive care medicine

Romain Sonneville, Eric Azabou, Pierre Bailly, Sarah Benghanem, Gilles De Almeida Cardoso, Pierre Claquin, David Cortier, Augustin Gaudemer, Bertrand Hermann, Pierre Jaquet, Virginie Lambrecq, Camille Legouy, Stéphane Legriel, Thomas Rambaud, Benjamin Rohaut, Benjamine Sarton, Stein Silva, Tarek Sharshar, Fabio Silvio Taccone, Dominique Vodovar, Nicolas Weiss, Charles Cerf

Anti-RNApol3-Associated myocarditis: an emerging disease linking autoimmunity and infection

Paul Quentric, Jean-Luc Charuel, Quentin Moyon, Guillaume Hékimian, Karim Dorgham, François Lifermann, Mathieu Kerneis, Alexis Mathian, Karim Aacha, Isabelle Melki, Juliette Chommeloux, Matthieu Petit, Melchior Gautier, Pierre Bay, Philippe Rouvier, Etienne Charpentier, Omaira da Mata-Jardin, Lucie Lefevre, Christophe Parizot, Ouriel Saura, David Levy, Sofia Ortuno, Matthieu Schmidt, Charles-Edouard Luyt, Guy Gorochov, Zahir Amoura, Alain Combes, Marc Pineton de Chambrun

Effect of manual decongestive therapy on cardiac preload in critically ill patients: a randomized controlled trial

  • Open Access
  • Edema
  • Research

Matthias J. Posch, Christian I. Schwer, Johannes Kalbhenn, Joachim Bansbach

Alterations in the renin-angiotensin system during septic shock

Camille Benaroua, Fabrizio Pucci, Marianne Rooman, Adrien Picod, Raphaël Favory, Matthieu Legrand, Jean-Louis Vincent, Jacques Creteur, Fabio Silvio Taccone, Filippo Annoni, Bruno Garcia

Selective decontamination regimens in French ICUs: association with reduced infection and resistance emergence

Nicolas Massart, Marc Leone, Florian Reizine, Gary Duclos, Anaïs Machut, Charles-Hervé Vacheron, Anne Savey, Emmanuelle Hammad, Arnaud Friggeri, Alain Lepape

Amikacin use in critically ill patients requiring renal replacement therapy: the AMIDIAL-ICU study

Vincent Dupont, Bruno Mourvillier, Coralie Barbe, Vincent Legros, Mathieu Jozwiak, Hamid Merdji, Claire Dupuis, Hadrien Winiszewski, Antoine Marchalot, Guillaume Lacave, Mathilde Neuville, Anne Sagnier, François Barbier, Carine Thivilier, Stéphanie Ruiz, Roland Smonig, Jeremy Rosman, Laurent Argaud, Steven Grangé, Benjamine Sarton, Patrick Chillet, Guillaume Voiriot, Lukshe Kanagaratnam, Zoubir Djerada

Ability of diastolic arterial pressure to better characterize the severity of septic shock when adjusted for heart rate and norepinephrine dose

Antoine Goury, Zoubir Djerada, Glenn Hernandez, Eduardo Kattan, Romain Griffon, Gustavo Ospina-Tascon, Jan Bakker, Jean-Louis Teboul, Olfa Hamzaoui

Correction: Effect of early and later prone positioning on outcomes in invasively ventilated COVID-19 patients with acute respiratory distress syndrome: analysis of the prospective COVID-19 critical care consortium cohort study

Andrew J. Simpkin, Bairbre A. McNicholas, David Hannon, Robert Bartlett, Davide Chiumello, Heidi J. Dalton, Kristen Gibbons, Nicole White, Laura Merson, Eddy Fan, Mauro Panigada, Giacomo Grasselli, Anna Motos, Antoni Torres, Ferran Barbé, Pauline Yeung Ng, Jonathon P. Fanning, Alistair Nichol, Jacky Y. Suen, Gianluigi Li Bassi, John F. Fraser, John G. Laffey

Combination of urinary biomarkers can predict cardiac surgery-associated acute kidney injury: a systematic review and meta-analysis

Nikolett Kiss, Márton Papp, Caner Turan, Tamás Kói, Krisztina Madách, Péter Hegyi, László Zubek, Zsolt Molnár

Time-dependent effects of prone position on ventilation-perfusion matching assessed by electrical impedance tomography in patients with COVID-19 ARDS: sub-analysis of a prospective physiological study

Yuxian Wang, Yaxiaerjiang Muhetaer, Xin Zheng, Wei Wu, Jiale Tao, Ling Zhu, Jieqiong Song, Zhanqi Zhao, Ming Zhong

Automatic continuous P0.1 measurements during weaning from mechanical ventilation: a clinical study

Flora Delamaire, Maamar Adel, Guillot Pauline, Quelven Quentin, Coirier Valentin, Painvin Benoit, Tadie Jean-Marc, Terzi Nicolas, Gacouin Arnaud

Does Levosimendan hasten veno-arterial ECMO weaning? A propensity score matching analysis

  • Open Access
  • ECMO
  • Research

Nicolas Paulo, Antoine Kimmoun, David Hajage, Pierre Hubert, David Levy, Marc Pineton de Chambrun, Juliette Chommeloux, Ouriel Saura, Grégoire Del Marmol, Quentin Moyon, Guillaume Hékimian, Melchior Gautier, Charles Edouard Luyt, Guillaume Lebreton, Bruno Levy, Alain Combes, Matthieu Schmidt

Impact of early versus conventional kidney replacement therapy initiation in tumor lysis syndrome: a target trial emulation

Justine Serre, Guillaume Mulier, Charlotte Boud’hors, Marie Lemerle, Moustafa Abdel-Nabey, Corentin Orvain, Anis Chaba, Lucie Biard, Julien Demiselle, Lara Zafrani

Visual coronary artery calcification score to predict significant coronary artery stenosis in patients presenting with cardiac arrest without ST-segment elevation myocardial infarction

Maxence Brunel, Brahim Harbaoui, Laurent Bitker, Carole Chambonnet, Matthieu Aubry, Loïc Boussel, Cyril Besnard, Jean-Christophe Richard, Pierre Lantelme, Pierre-Yves Courand

Comparison of all-cause mortality with different blood glucose control strategies in patients with diabetes in the ICU: a network meta-analysis of randomized controlled trials

  • Open Access
  • Research

Xi Li, Jiahao Meng, Xingui Dai, Pan Liu, Yumei Wu, Shuhao Wang, Heng Yin, Shuguang Gao

Impact of aminoglycosides on survival rate and renal outcomes in patients with urosepsis: a multicenter retrospective study

David Rozenblat, Arnaud Serret-Larmande, Alexis Maillard, Romain Arrestier, Sarah Benghanem, Julien Charpentier, Michael Darmon, Vincent Das, François Dépret, Jean Luc Donay, Hervé Jacquier, Hélène Poupet, Jean-Michel Molina, Matthieu Lafaurie

Alcohol related hepatitis in intensive care units: clinical and biological spectrum and mortality risk factors: a multicenter retrospective study

Maxime Gasperment, Léa Duhaut, Nicolas Terzi, Côme Gerard, Luc Haudebourg, Alexandre Demoule, Mialy Randrianarisoa, Vincent Castelain, Sacha Sarfati, Fabienne Tamion, Charlene Le Moal, Christophe Guitton, Gabriel Preda, Arnaud Galbois, Thibault Vieille, Gaël Piton, Marika Rudler, Guillaume Dumas, Hafid Ait-Oufella

Stewart’s theory and acid–base changes induced by crystalloid infusion in humans: a randomized physiological trial

  • Open Access
  • Research

Antonio Maria Dell’Anna, Domenico Luca Grieco, Cristina Dominedò, Marta Cicetti, Irene Cisterna, Rossano Festa, Rosa Lamacchia, Giuseppina Giannì, Nicoletta Filetici, Teresa Michi, Cristina Rossi, Francesca Danila Alcaro, Alessandro Mele, Aurora Rocchi, Demetrio Del Prete, Maria Concetta Meluzio, Francesco Ciro Tamburrelli, Marco Rossi, Massimo Antonelli

Use of procalcitonin in therapeutic decisions in the pediatric intensive care unit

Pierre Tissières, Elisabeth Esteban Torné, Johannes Hübner, Adrienne G. Randolph, Corsino Rey Galán, Scott L. Weiss

Nirsevimab prophylaxis on pediatric intensive care hospitalization for severe acute bronchiolitis: a clinical and economic analysis

Sarah Touati, Alexandre Debs, Luc Morin, Laure Jule, Caroline Claude, Pierre Tissieres, Melissa Beggaz, Matthieu Blanc, Claire Boithias, Charlotte Brognion, Diane Carriere, Ramy Charbel, Mafoudia Conde, Vladimir L Cousin, Narjess Ghali, Clémence Marais, Jordi Miatello, Francisco Oddone, Pierre Tissières

Epidemiology and prediction of non-targeted bacteria by the filmarray pneumonia plus panel in culture-positive ventilator-associated pneumonia: a retrospective multicentre analysis

F. Berteau, A. Kouatchet, Y. Le Gall, C. Pouplet, A. Delbove, C. Darreau, J. Lemarie, F. Jarousseau, F. Reizine, C. Giacardi, G. Allo, C. Aubron, M. Eveillard, V. Dubee, R. Mahieu

Correction: Impact of frailty and older age on weaning from invasive ventilation: a secondary analysis of the WEAN SAFE study

  • Open Access
  • Correction

Caoimhe M. Laffey, Rionach Sheerin, Omid Khazaei, Bairbre A. McNicholas, Tài Pham, Leo Heunks, Giacomo Bellani, Laurent Brochard, Dana Tomescu, Andrew J. Simpkin, John G. Laffey

Hemodynamic effects of adjunct arginine vasopressin to norepinephrine in septic shock: insights from a prospective multicenter registry study

Max Melchers, Vivienne de Smet, Chrissie Rooijakkers, Jonathan Huising, Wander Vermeulen, Beyza Nur Nisa Köktaş, Karlijn Johanna van de Vusse, Kimia Milani Sabzewar, Shakti Bedanta Mishra, Carina Bethlehem, Dirk P. Boer, Nedim Cimic, Mirella van Duijnhoven, Tim Frenzel, Jordi Liesveld, Gianluca Paternoster, Susanne Stads, Jan J. Weenink, Barbara Festen-Spanjer, Peter Pickkers, Arthur Raymond Hubert van Zanten

Predicting intrathecal immunoglobulin synthesis in the ICU: a comparative study of IgG-based indexes

Alexander Balcerac, Clémence Marois, Delphine Sterlin, Benjamin Rohaut, Sophie Demeret, Nicolas Weiss, Loic Le Guennec

Nosocomial lower respiratory tract infections in patients with immunosuppression: a cohort study

Luis Felipe Reyes, Natalia Sanabria-Herrera, Saad Nseir, Otavio T. Ranzani, Pedro Povoa, Emilio Diaz, Marcus J. Schultz, Alejandro Rodríguez, Cristian C. Serrano-Mayorga, Gennaro De Pascale, Paolo Navalesi, Szymon Skoczynski, Mariano Esperatti, Luis Miguel Coelho, Andrea Cortegiani, Stefano Aliberti, Anselmo Caricato, Helmut J. F. Salzer, Adrian Ceccato, Rok Civljak, Paolo Maurizio Soave, Charles-Edouard Luyt, Pervin Korkmaz Ekren, Fernando Rios, Joan Ramon Masclans, Judith Marin, Silvia Iglesias-Moles, Stefano Nava, Davide Chiumello, Lieuwe D. J. Bos, Antonio Artigas, Filipe Froes, David Grimaldi, Mauro Panigada, Fabio Silvio Taccone, Massimo Antonelli, Antoni Torres, Ignacio Martin-Loeches

Right atrial presssure and intra-abdominal pressure: the elephant in the room

  • Open Access
  • Letter to the Editor

Ngan Hoang Kim Trieu

Impact of substance use disorders on critical care management and health outcomes in septic adolescents

Havell Markus, Gary D. Ceneviva, Neal J. Thomas, Conrad Krawiec

High flow nasal therapy versus noninvasive ventilation for AECOPD with acute hypercapnic respiratory failure: a meta-analysis of randomized controlled trials

Jinlv Qin, Guizuo Wang, Yixing Liao, Wenli Shang, Dong Han

Immediate or delayed initiation of renal replacement therapy in patients with leptospirosis and acute kidney injury: a target trial emulation

Marie Julien, Cédric Rafat, Loïc Raffray, Henri Vacher-Coponat, Nicolas Allou, Jérôme Allyn, Julien Jabot, Yannis Lombardi

Confounding by indication and exposure misclassification may undermine corticosteroid effect estimates in ICU patients with alcohol-related hepatitis

Dongxu Mao, Min Li

Critical insights for intensivists on Guillain-Barré syndrome

Nicolas Weiss, Clémence Marois, Loic Le Guennec, Benjamin Rohaut, Sophie Demeret

Association of metformin administration after septic shock with short-term and long-term survival in septic shock patients with diabetes

Bo-Yeong Jin, Sukyo Lee, Woosik Kim, Jong-Hak Park, Hanjin Cho, Sungwoo Moon, Sejoong Ahn

Association between ventilation–perfusion matching improvement during initial prone positioning and ICU mortality in patients with moderate to severe ARDS: a prospective two-center study

Rui Wang, Wancong Wang, Xiao Tang, Zhenyuan Qi, Ting Li, Yalan Liu, Hongju Li, Jican Yan, Hua Yang, Wenrui Lyu, Zhaohong Li, Bing Sun, Guifen Gan

Response letter to “Confounding by indication and exposure misclassification may undermine corticosteroid effect estimates in ICU patients with alcohol-related hepatitis”

Guillaume Dumas, Maxime Gasperment, Hafid Ait-Oufella

Factors influencing the transition phase in acute respiratory distress syndrome: an observational cohort study

Anne-Fleur Haudebourg, Louise Chantelot, Safaa Nemlaghi, Luc Haudebourg, Pascale Labedade, Mohamed Ahmed Boujelben, Guillaume Voiriot, Armand Mekontso Dessap, Muriel Fartoukh, Guillaume Carteaux

Characteristics of SARS-CoV-2-associated severe episodes of monoclonal gammopathy-associated capillary leak syndrome (Clarkson disease)

Nissim Grinberg, Maddalena Alessandra Wu, Quentin Moyon, Sybille Merceron, Yannick Fedun, Marie Gousseff, Romain Sonneville, François Lhote, Elie Azoulay, Jean-Herlé Raphalen, David Saadoun, Ygal Benhamou, Jean-Paul Mira, Guillaume Dumas, Pierre Bay, Jérôme Devaquet, Laurent Argaud, Marc Lambert, Avinash Aujayeb, Basile Henriot, Amandine Bichon, Thomas Bocar, John Harty, Remo Melchio, Franck Leibinger, Laure Calvet, Tomas Urbina, Laurent Bodson, Jean-Marie Tonnelier, Danielle Reuter, Emmanuel Canet, Gilles Blaison, Julien Maizel, Nicholas Sedillot, Laurence Dangers, Vincent Eble, Franco Verlicchi, Stanislas Faguer, Jonathan Montomoli, Geoffroy Dingemans, Marc Mikulski, Jonas Pochard, Fabrice Uhel, Fleur Cohen-Aubart, Charles-Edouard Luyt, Alexis Mathian, Alain Combes, Riccardo Colombo, Zahir Amoura, Marc Pineton de Chambrun

Hospitalization of very old critically ill patients in medical intermediate care units in France: a nationwide population-based study

  • Open Access
  • Research

Adrien Migeon, Arthur Kassa-Sombo, Emeline Laurent, Lucile Godillon, Leslie Grammatico-Guillon, Antoine Guillon

Guidelines for the management of emergencies and critical illness in pediatric and adult patients with sickle cell disease

Armand Mekontso Dessap, Stephane Dauger, Mehdi Khellaf, Maite Agbakou, Sophie Agut, François Angoulvant, Jean-Benoît Arlet, Cécile Aubron, Florent Baudin, Florence Boissier, Nicolas Bounaud, Pierre Catoire, Jérôme Cecchini, Djamila Chaiba, Anthony Chauvin, Richard Chocron, Benedicte Douay, Delphine Douillet, Narcisse Elenga, Olivier Flechelle, Ségolène Gendreau, Sybille Goddet, Jeremy Guenezan, Anoosha Habibi, Claire Heilbronner, Bérengère Koehl, Pierrick Le Borgne, Philippe Le Conte, Annick Legras, Michael Levy, Bernard Maitre, Mathieu Oberlin, Mehdi Oualha, Nicolas Peschanski, France Pirenne, Corinne Pondarre, Jérôme Rambaud, Keyvan Razazi, Geoffroy Rousseau, Aurélie Schirmann, Isabelle Thuret, Ruddy Valentino, Guillaume Voiriot, Barbara Villoing, Marion Grimaud, Sandrine Jean

Absolute blood levels and kinetics of neurofilament light (NFL) chains for neurological prognosis in comatose patients after cardiac arrest

Timothée Ayasse, Maxime Touron, Marie-Céline Blanc, Estelle Pruvost-Robieux, Jean-Baptiste Lascarrou, Clara Vigneron, Jean-Paul Mira, Frédéric Pène, Alain Cariou, Sarah Benghanem

Physiological complexities of intraabdominal hypertension: taming the elephant

  • Open Access
  • Letter to the Editor

S Magder

Critically ill patients with necrotizing soft tissue infections in the Caribbean area: unsupervised analysis of a retrospective cohort (2014–2023) with identification of factors associated with mortality

Jean-David Pommier, Benoît Tressieres, Pascal Blanchet, Frederic Desmoulins, Pascale Piednoir, Nejla Aissa, Frederic Martino, Marc Valette, Alexandre Demoule, Sebastien Breurec, Laurent Camous

Lipidomic signatures of ventilator-associated pneumonia in COVID-19 ARDS patients: a new frontier for diagnostic biomarkers

Arthur Kassa-Sombo, Charles Verney, Augustin Pasquet, Julien Vaidie, Deborah Brea, Virginie Vasseur, Adeline Cezard, Antoine Lefevre, Camille David, Eric Piver, Lydie Nadal-Desbarats, Patrick Emond, Hélène Blasco, Mustapha Si-Tahar, Antoine Guillon

Vascular leakage during circulatory failure: physiopathology, impact and treatments

Jérémie Joffre, Peter Radermacher, Hatem Kallel, Iris Marangon, Alexandre Rutault, Yaël Levy, Alexandre Gaudet, Benjamine Sarton, Louis Kreitmann, Lucillia Bezu, Meryl Vedrenne, Thomas Maldiney, Youenn Jouan, Sarah Benghanem, Laure Stiel, Stéphane Germain, Nicolas Bréchot

Post-mortem lung biopsies in fatal Covid-19 acute respiratory distress syndrome: a prospective cohort study of 169 patients (HISTOCOVID)

Jean Morin, Christine Sagan, Morgane Pere, Riad Chelha, Pierre Yves Olivier, Georges Simon, Marion Rougon, Frédéric Pène, Alexis Ferre, Toufik Kamel, Alexandre Boyer, Julio Badie, Jan Hayon, Maxens Decavèle, Pierre Garçon, Jean-Christophe Richard, Laurent Argaud, Sami Hraiech, Johann Auchabie, Camille Foucault, François Legay, Paul-Marie Chanareille, Bertrand Souweine, Guillaume Géri, Agathe Delbove, Vincent Bonny, Pascal Beuret, Damien Vimpere, Gaëtan Plantefève, Emmanuel Canet

Decoding portal vein pulsatility: hemodynamic determinants in a post-hoc analysis of a prospective observational trial

Cosmin Balan, Bianca Morosanu, Antonia Fodoroiu, Vlad Dobre, Andrei Dumitrache, Robert Thomas Barbulescu, Liana Valeanu, Cornel Robu, Cristian Boros, Alexandru Nica, Adrian Wong, Francesco Corradi, Ioana Marina Grintescu, Serban-Ion Bubenek-Turconi

Correction: Automatic continuous P0.1 measurements during weaning from mechanical ventilation: a clinical study

  • Open Access
  • Correction

Flora Delamaire, Maamar Adel, Guillot Pauline, Quelven Quentin, Coirier Valentin, Painvin Benoit, Tadie Jean-Marc, Terzi Nicolas, Gacouin Arnaud

Attenuation of the plasma volume response to crystalloid fluid used for goal-directed fluid therapy

  • Open Access
  • Research

Robert G. Hahn, Terry O’Brien

Impact of awake prone positioning duration on intubation or mortality in COVID-19 patients with acute respiratory failure: secondary analysis of a randomized clinical trial

Qin Sun, Rui Zhang, Junyi Zhang, Jianfeng Xie, Yingzi Huang, Yi Yang, Haibo Qiu, Ling Liu, Hui Chen

Prognosis of Nonagenarian ICU Patients A Bayesian analysis of prospective European studies

  • Open Access
  • Research

Daniel Dankl, Raphael Romano Bruno, Michael Beil, Hans Flaatten, Malte Kelm, Sviri Sigal, Wojciech Szczeklik, Muhammed Elhadi, Michael Joannidis, Andreas Koköfer, Barbara Schreiber, Franz Singhartinger, Sandra Oeyen, Brian Marsh, Rui Moreno, Susannah Leaver, Dylan W De Lange, Bertrand Guidet, Ariane Boumendil, Christian Jung, Bernhard Wernly

Biomarkers for intensive care unit-acquired weakness: a systematic review for prediction, diagnosis and prognosis

Jiamei Song, Ting Deng, Qingmei Yu, Xun Luo, Yanmei Miao, Leiyu Xie, Yongming Mei, Peng Xie, Shaolin Chen

High-flow nasal therapy versus non-invasive ventilation for AECOPD: navigating beyond a simple choice– are we asking the right questions??

Mauro Castro Sayat, Nicolás Colaianni-Alfonso, Adrián Gallardo, Luigi Vetrugno

Adherence to post-cardiac arrest care guidelines and impact on survival and neurological outcome

Giulia Merigo, Fabiana Madotto, Aurora Magliocca, Gaetano Florio, Alessandra Rosati, Valentina Castagna, Marco Pagliano, Alberto Zanella, Mauro Panigada, Giacomo Grasselli, Giuseppe Ristagno

Is high flow nasal therapy still warranted for patients with AECOPD and acute hypercapnic respiratory failure?

  • Open Access
  • Letter to the Editor

Jinlv Qin, Guizuo Wang, Yixing Liao, Wenli Shang, Dong Han

Omics approach to chest electrical impedance tomography reveals physiological cluster of ARDS characterised by increased respiratory drive and effort

Tommaso Mauri, Marco Leali, Elena Spinelli, Gaetano Scaramuzzo, Massimo Antonelli, Domenico L. Grieco, Savino Spadaro, Giacomo Grasselli

Platelet transfusion practice in the intensive care unit: the Nine-I international platelet transfusion survey

Lene Russell, Elie Azoulay, Carl Thomas Anthon, Frédéric Pène, Padmastuti Akella, Asma Mabrouki, Kathryn Puxty, Lene Bjerregaard Nielsen, Jo Bønding Andreasen, Thomas Kander, Fredrik Sjövall, Johanna Hästbacka, Christine Lodberg Hvas, Andry Van De Louw, Sanjay Chawla, Philippe R. Bauer, Pedro Castro, Pedro Povoa, Luis Coelho, Sara Fernandez, Arzu Topeli, Andreas Barratt-Due, Caterina Barbaglio, Matthias Kochanek, Ignacio Martin-Loeches, Nancy Kentish-Barnes

Endotoxin removal by the OXIRIS filter for cardiogenic shock requiring veno-arterial extra-corporeal life support: the ECMORIX randomized controlled trial

Maxime Nguyen, Marvin Alvarez, Corentin Evezard, Vivien Berthoud, Damien Leleu, Jean-Paul Pais-De-Barros, Olivier Bouchot, Osama Abou-Arab, Belaid Bouhemad, David Masson, Thomas Gautier, Pierre-Grégoire Guinot

Intra-hospital transport of adult critically ill patients treated with high flow nasal cannula oxygen: a prospective observational multicenter study

Mai-Anh Nay, Alice Bisson, Adrien Auvet, Agathe Delbove, Aziz Berrouba, Toufik Kamel, Maxime Desgrouas, Thierry Boulain

Sex differences in advance directives and their clinical translation among critically ill adults: results from the ADVISE study

Simon A. Amacher, Sira M. Baumann, Paulina S. C. Kliem, Dominik Vock, Yasmin Erne, Pascale Grzonka, Sebastian Berger, Martin Lohri, Sabina Hunziker, Caroline E. Gebhard, Mathias Nebiker, Luca Cioccari, Raoul Sutter

Weaning from mechanical ventilation in myasthenic crisis according to WEAN safe: most patients experience intermediate or prolonged weaning with no differences between early and late-onset compared to very-late onset myasthenia Gravis

Clémence Marois, Arthur Combes, Meriem Bouguerra, Alexandra Grinea, Lucas Di Meglio, Thomas Rambaud, Loïc Le Guennec, Francis Bolgert, Benjamin Rohaut, Sophie Demeret, Nicolas Weiss

Vascular hyporesponsiveness to norepinephrine is a major but not exclusive determinant of mortality in septic shock

Antoine Goury, Zoubir Djerada, Jean-Louis Teboul, Olfa Hamzaoui

Crosstalk between lung and extrapulmonary organs in sepsis-related acute lung injury/acute respiratory distress syndrome

Bingyu Li, Weishan Lin, Ruomeng Hu, Songjie Bai, Yejiao Ruan, Yushi Fan, Shuya Qiao, Xuehuan Wen, Ruishan Liu, Heyu Chen, Wei Cui, Zhijian Cai, Gensheng Zhang

Hyperglycemia and insulin use in patients with COVID-19 and severe hypoxemia allocated to 12 mg vs. 6 mg of dexamethasone: a secondary analysis of the COVID STEROID 2 randomized trial

Clara Lundetoft Clausen, Thomas Bryrup, Christian Leo Hansen, Daniel Faurholt-Jepsen, Alessandra Meddis, Thomas Peter Almdal, Ole Snorgaard, Henrik Løvendahl Jørgensen, Marie Helleberg, Margit Smitt, Christian Aage Warmberg, Klaus Tjelle, Charlotte Suppli Ulrik, Anne Sofie Andreasen, Morten Bestle, Lone Poulsen, Klaus Vennick Marcussen, Lothar Wiese, Marie Warrer Munch, Anders Perner, Rikke Krogh-Madsen, Thomas Benfield

Expert consensus‑based clinical practice guidelines for nutritional support in the intensive care unit: the French Intensive Care Society (SRLF) and the French-Speaking Group of Pediatric Emergency Physicians and Intensivists (GFRUP)

Jean Reignier, Benedicte Gaillard-Le Roux, Pierre François Dequin, Valeria A. Bertoni Maluf, Julien Bohe, Michael P. Casaer, Agathe Delbove, Claire Dupuis, Eric Fontaine, Prescillia Gamon, Coralie Grange, Nicholas Heming, Melissa Jezequel, Adam Jirka, Corinne Jotterand Chaparro, Michael Landais, Nolwenn Letouze, Claire Morice, Olivier Pantet, Julie Pellecer, Gael Piton, Shancy Rooze, Julie Starck, Jean-Marc Tadie, Fabienne Tamion, Ronan Thibault, Frédéric Valla, Thierry Vanderlinden, Arnaud W. Thille, Nadia Aissaoui

Renal replacement therapy in an intensive care unit: guidelines from the SRLF-GFRUP consensus conference

Mercè Jourdain, Ines Gragueb Chatti, Brahim Housni, Pierre Jaquet, Mélissa Jezequel, Oumar Kane, Béatrice La Combe, Mickael Landais, Mehdi Marzouk, Etienne de Montmollin, Guillaume Mortamet, Mai-Anh Nay, Charlotte Salmon-Gandonnière, Sophie Perinel-Ragey, Jérôme Rambaud, Joanna Schmitt, Marie Simon, Julie Starck, Arnaud W. Thille, Pierre-François Dequin

Neuroimaging for prognosis of central nervous system infections: a systematic review and meta-analysis

Augustin Gaudemer, Netanel Covier, Marie-Cécile Henry-Feugeas, Jean-François Timsit, Philippa Catherine Lavallée, Etienne de Montmollin, Augustin Lecler, Antoine Khalil, Romain Sonneville, Camille Couffignal

How should spontaneous breathing trials be performed in the light of recent literature?

  • Open Access
  • Editorial

Arnaud W. Thille, Gonzalo Hernández

Biomarkers to guide sepsis management

Vasiliki Bourika, Evangelia-Areti Rekoumi, Evangelos J. Giamarellos-Bourboulis

Angiotensin II, conventional vasopressor therapy, and mortality in shock: a large, multicenter, propensity score-weighted analysis

  • Open Access
  • Shock
  • Research

Laurence W. Busse, Caitlin ten Lohuis, Han Xu, Cooper Jannuzzo, Robert H. Lyles, J. Pedro Teixeira, Ishan Mehta, Yuan Liu

Association between the Venous Excess Ultrasound (VExUS) score and acute kidney injury in critically ill patients with sepsis: a multicenter prospective observational study

Jia Song, Gongze Chen, Detian Lai, Li Zhong, Haozhe Fan, Weihang Hu, Minjia Wang, Caibao Hu, Wenwei Chen, Ziqiang Ming, Shijin Gong, Qiancheng Luo

Awareness, knowledge and practices related to intra-abdominal hypertension and abdominal compartment syndrome among intensive care providers: a systematic scoping review

ZhiRu Li, FangYan Lu, JingYun Wu, YanHong Dai, Yan Wang, Li Zheng, HuaFen Wang

Regarding the new vascular reactivity index to norepinephrine

  • Open Access
  • Letter to the Editor

Enrique Monares-Zepeda, Christopher Barrera-Hoffmann

Refining thresholds and timing in V/Q matching assessment during prone positioning in ARDS

Nan Xiong, Yinde Huang

Metabolomic stratification of shock: pathophysiological insights for personalized critical care

  • Open Access
  • Shock
  • Research

Frederic Sangla, Karim Bendjelid, Federico Aletti, Vicente Ribas, Antoine Herpain, Bernardo Bollen Pinto, David Legouis

Utility of fibrinolysis enhanced viscoelastic assays to evaluate fibrinolysis disorders in critically ill adults with severe infection: a scoping review

Matthew Self, Lucy A. Coupland, Anders Aneman

Physiological and clinical effects of two ultraprotective ventilation strategies in patients with veno-venous extracorporeal membrane oxygenation: the ECMOVENT study

  • Open Access
  • ECMO
  • Research

Yorick Rodriguez, Alexandre Thomachot, Guillaume Deniel, Mehdi Mezidi, Louis Chauvelot, Hodane Yonis, Jean-Christophe Richard, Laurent Bitker

IFNγ in human sepsis: a scoping review

Daniel Thomas-Rüddel, Evangelos Giamarellos-Bourboulis, Caroline Neumann, Josef Briegel, Antoine Roquilly, Djillali Annane, Reinhard Wetzker, Michael Bauer, Sara Aly Abdelghany, Maha Khalaf AlyAly, Mohamed Gamal Elansary, Shereen Mustafa Elgengeehy, Heba Mostafa Elwi, Yasser Sadek Nassar, Rania Yehia Hash, Rania Bouneb, Zaineb Chelly-Dagdia, Katy Diallo, Jérome Fleuriet, Henri-Jean Garchon, Stanislas Grassin Delyle, Rahma Hellali, Nicholas Heming, Nicolas Hunzinger, Elodie Lamy, Jihene Mahmoud, Virginie Maxime, Pierre Moine, Camille Roquencourt, Marie Alice Vovy, Karine Zeitouni, Manuela Adling-Ehrhardt, Frank Bloos, Sandra Frank, Katharina Habler, Ludwig Hinske, Rainer König, Dorothea Lange, Margit Leitner, Marcus Oswald, Christina Scharf-Janssen, ichael Vogeser, Carlos Flores, Jesús Villar

Revisiting awake prone positioning in COVID-19

  • Open Access
  • COVID-19
  • Letter to the Editor

Yisheng Cao, Qianqian Mao

Respiratory management of critically ill pneumocystis pneumonia patients: a multicenter retrospective study

Florian Reizine, Vicky Stiegler, Romain Lécuyer, Benoit Tessoulin, Marie Gallais, Fabrice Camou, Florent Morio, Anne Cady, Frederic Gabriel, Emmanuel Canet, François Raffi, David Boutoille, Nahéma Issa, Benjamin Gaborit, Charlotte Biron, Maeva Lefebvre, Benjamin Jean Gaborit, Paul Le Turnier, Colin Deschanvres, Raphael Lecomte, Marie Chauveau, Antoine Asquier-Khati, Valentin Pineau, Marie Prime, Clarisse Delaunay, Hakim Essid, Vicky Steigler, Patrice Le Pape, Rose-Anne Lavergne, Fakhri Jeddi, Stéphane Corvec, Pascale Bemer, Jocelyne Caillon, Aurélie Guillouzouic, Anne-Gaëlle Leroy, Karim Lakhal, Raphaël Cinotti, Antoine Roquilly, Mickael Vourc’h, Jean Reignier, Soraya Benguerfi, François Xavier Blanc, Cédric Bretonniere, Jean Morin, Camille Le Blanc, Hakim Alami, Olivier Guisset, Gaelle Mourissoux, Isabelle Accoceberry, Noémie Coron, Laurence Delhaes, Sébastien Imbert, Maxime Lefranc, Florian Lussac-Sorton, Amandine Rougeron, Marie Gousseff, Yoann Crabol, Grégory Corvaisier, Florent Lautredoux, Myriam Auger, Pascal Pouedras

Renal perfusion pressure: role and implications in critical illness

Rakshit Panwar, Bairbre McNicholas, J. Pedro Teixeira, Amit Kansal

Immunosuppressive therapy management during sepsis in kidney transplant recipients: a prospective multicenter study

Valentin Rivet, Adrien Joseph, Romain Arrestier, Laure Calvet, Anne-Sophie Moreau, Côme Bureau, Laurent Argaud, Paul Gabarre, Benjamin Zuber, Jean-Herlé Raphalen, Stéphanie Pons, Raphaël Clere-Jehl, Lara Zafrani

Assessing the carbon footprint of the initial 24 h post-severe trauma admission in a French ICU: a pilot study

Candice Marion, Matthieu Bernat, Emmanuelle Hammad, Jean-Paul Calvet, Manon Roche, Ludivine Marecal, Laurent Zieleskiewicz, Marc Leone

Refining APP strategies in COVID-19: balancing efficacy, feasibility, and individual needs

Qin Sun, Hui Chen, Yi Yang, Haibo Qiu, Ling Liu

PEEP in SBTs: breathing and beyond

  • Open Access
  • Letter to the Editor

Ichita Yamamoto, Yasuhiro Norisue

Population-wise incidence and outcomes of patients requiring invasive and non-invasive mechanical ventilation in China: a nationwide retrospective analysis by age, sex, and comorbidity

Maomao Cao, Rong Liufu, Boyang Wang, Wei Pan, Hongda Chen, Longxiang Su, Yun Long, Xiang Zhou, Li Weng, Bin Du

Maximal inspiratory diaphragmatic ultrasound predicts postoperative pulmonary complications after upper abdominal surgery

Ting Yan, Qing Yu, Chun-Qing Li, Zhen-Zhen Xu, Jia-Hui Ma, Min Xie, Sai-Nan Zhu, Dong-Xin Wang, Shuang-Ling Li

Impact of therapeutic hypothermia on cardiogenic shock outcomes: a systematic review and meta-analysis

Miloud Cherbi, Bruno Levy, Paul Gautier, Nadia Aissaoui, Pierre-Grégoire Guinot, Hamid Merdji, Clément Delmas

Diagnostic yield and adverse events of liver biopsy in intensive-care-unit patients: a multicenter retrospective observational cohort study

Mégane Charrier, Jean-Claude Lacherade, Lara Zafrani, Jérôme Hoff, Jean Reignier, Jean-Baptiste Lascarrou, Jean-François Mosnier, Emmanuel Canet

Transplant-free survival in acute liver failure patients receiving MARS®, plasma exchange or no liver support. A real-life 21-year retrospective cohort study in a referral center

  • Open Access
  • Research

Kieran Pinceaux, Félicie Bélicard, Valentin Coirier, Estelle Le Pabic, Pauline Guillot, Flora Delamaire, Benoît Painvin, Quentin Quelven, Mathieu Lesouhaitier, Adel Maamar, Arnaud Gacouin, Pauline Houssel-Debry, Karim Boudjema, Edouard Bardou-Jacquet, Jean-Marc Tadié, Florian Reizine, Christophe Camus

Urinary 3-methylhistidine as a potential biomarker for sepsis-associated acute kidney injury: multidimensional metabolomics analysis in mice and human

Xibo Wang, Pengfei Huang, Yinghao Luo, Yu Xin, Yue Li, Lifeng Shen, Yanqi Liu, Yang Zhou, Yuxin Zhang, Qianqian Zhang, Dawei Wang, Feiyu Luan, Weiting Zhang, Mengyao Yuan, Yuhan Liu, Fengye Liu, Nan Zhang, Jinyuan Wu, Tao Wu, Xuan Wang, Yuping Bai, Mingyan Zhao, Changsong Wang, Kaijiang Yu

Serum proteomes and their prognostic values in sepsis patients admitted to a medical intensive care unit: a single-center study using SWATH-MS proteomics

Su Yeon Lee, Jee Hwan Ahn, Sang-Bum Hong, Dong-Gon Hyun, Chae-Man Lim, Kyunggon Kim, Jin Won Huh

Lung electrical impedance tomography during positioning, weaning and chest physiotherapy in mechanically ventilated critically ill patients: a narrative review

Sam Bayat, Claude Guérin, Bruno Louis, Nicolas Terzi

Neurally adjusted ventilatory assist in critical care patients with and without obesity: a prospective randomized crossover study

Matthieu Conseil, Samir Jaber, Fabrice Galia, Nicolas Molinari, Gerald Chanques, Audrey De Jong, Mathieu Capdevila

Selective digestive decontamination

Bernard Allaouchiche

More intravascular volume, less edema: pressure therapy for the management of capillary leakage and fluid accumulation

  • Open Access
  • Edema
  • Letter to the Editor

Auguste Dargent, Vanessa Louzier, Jean-Pierre Quenot

From leptospirosis-induced AKI to AKI at large: the ongoing search for biomarkers to guide RRT initiation

  • Open Access
  • Letter to the Editor

Marie Julien, Yannis Lombardi, Julien Jabot, Cédric Rafat

Reconsidering early RRT in leptospirosis AKI: a question of timing criteria

  • Open Access
  • Letter to the Editor

Pei-Chen Wu, Thomas Tao-Min Huang

Harnessing artificial intelligence to address substance use disorders in critically ill adolescents: a synergistic approach

Zekai Yu

Advancing future research on sepsis outcomes in adolescents with SUD: integrating AI, accounting for temporal trends, and enhancing exposure classification

Havell Markus, Gary D. Ceneviva, Neal J. Thomas, Conrad Krawiec

The intricate relationship between capillary refill time and systemic hemodynamics in septic shock

Glenn Hernandez, Eduardo Kattan, Gustavo Ospina-Tascón, Sebastian Morales, Nicolás Orozco, Gustavo García-Gallardo, Macarena Amthauer, Jing-Chao Luo, Jan Bakker

Adherence assessment in post-cardiac arrest care: are physiological targets sufficient?

  • Open Access
  • Letter to the Editor

George Mannu

Severe hemoptysis: etiologies, management, and outcomes from a single-center experience over the last decade

Julien Dessajan, Aude Gibelin, Matthias Barral, Nina de Montmollin, Vincent Labbé, Michel Djibré, Guillaume Voiriot, Matthieu Turpin, Antoine Parrot, Muriel Fartoukh

Mental health outcomes at intensive care unit discharge: prevalence, mediators and risk factors

Maryline Couette, Segolene Gendreau, Marie Charlotte Boishardy, Anne-Fleur Jean Baptiste, Paula Xavier, Keyvan Razazi, Romain Arrestier, Guillaume Carteaux, Nicolas De Prost, Stephane Mouchabac, Florian Ferreri, Armand Mekontso Dessap

Hitting the target or missing the point? A closer look at post–cardiac arrest guideline adherence

  • Open Access
  • Letter to the Editor

Giulia Merigo, Fabiana Madotto, Aurora Magliocca, Giuseppe Ristagno

Authors reply in response to a letter on “impact of aminoglycosides on survival rate and renal outcomes in patients with urosepsis: a multicenter retrospective study”

David Rozenblat, François Dépret, Matthieu Lafaurie

Sepsis-induced myocardial dysfunction diagnosed with strain versus non-strain echocardiography parameters: incidence, evolution and association with prognosis

Filipe André Gonzalez, Jacobo Bacariza, Ana Rita Varudo, João Leote, Ricardo Meireles Mateus, Cristina Maia Martins, Maria Inês Ribeiro, Filippo Sanfilippo, Luís Rocha Lopes, Ana G. Almeida

Use of CO2-derived variables in critically ill patients

Jihad Mallat, Mathieu Jozwiak, Nicolás Orozco, Olfa Hamzaoui, Xavier Monnet, Jean-Louis Teboul, Daniel De Backer, Gustavo A. Ospina-Tascón

Impact of early PaCO2 and pH fluctuations on neurological outcomes in ARDS patients receiving VV ECMO: a retrospective cohort study from the CSECLS registry

  • Open Access
  • ECMO
  • Research

Xiaoli Chen, Jinquan Xie, Ya Wang, Zhongtao Du, Xinyi Luo, Zitao Zeng, Haixiu Xie, Jinxiang Ma, Zhangwei Liang, Yin Xi, Jie Zhang, Weibo Liang, Chenglong Li, Zhenting Liang, Jiao Li, Weiqun He, Xiaoqing Liu, Yimin Li, Xiaotong Hou, Yonghao Xu

Exogenous corticosteroid-induced modulation of RAAS: potential implications for septic shock biomarker analysis

Thomas Uslar, Benjamin Sanfuentes, Rene Baudrand, Glenn Hernández, Eduardo Kattan

Selective decontamination regimens in French ICUs: author’s response

Nicolas Massart, Marc Leone, Alain Lepape

Bereavement interventions for families in the ICU: a scoping review informed by a core outcome set

  • Open Access
  • Research

Sarah Foran, Mah Rukh, Alison Knapp, Jennifer M. O’Brien, Carol Brons, Janelle Glessman, Joann Kawchuk, Donna Goodridge, Sabira Valiani

Rethinking the “transition phase” in ARDS: can we afford to overlook the physiology behind NMBA weaning and PSV failure??

Nan Xiong, Yinde Huang

Transition phase in acute respiratory distress syndrome: paving the way for our next major challenge

Anne-Fleur Haudebourg, Guillaume Carteaux

Mechanical power normalisation methods to predict ICU mortality: a retrospective cohort study

Reza Khorasanee, Barnaby Sanderson, Emilia Tomarchio, Patrick D. Collins, Riccardo Del Signore, Sridevi Shetty, Mara Chioccola, Francesca Pugliese, Francesca Collino, Louise Rose, Lorenzo Giosa, Luigi Camporota

Circulating biomarkers of vasoplegia: a systematic review

Naomi Boyer, Prateek Upadhyay, Megan H. Hicks, Alexander Zarbock, Ashish K. Khanna, Lui G. Forni, Benedict C. Creagh-Brown

Tidal volume and mortality during extracorporeal membrane oxygenation for acute respiratory distress syndrome: a multicenter observational cohort study

  • Open Access
  • ECMO
  • Research

Torben M. Rixecker, Jeannine L. Kühnle, Johannes Herrmann, Christopher Lotz, Christian Kühn, Frederik Seiler, Carlos Metz, Armin Kalenka, Oxana Mazuru, Kai Borchardt, Ralf M. Muellenbach, Robert Bals, Matthieu Schmidt, Patrick Meybohm, Vitalie Mazuru, Philipp M. Lepper, Janno Schade, Noah Paschke, Martha E. Hübsch, Quirin Notz, Daniel Röder, Peter Kranke, Michaela L. Merten, Micha Landoll, Peter Spieth, Stefan Kluge, Dominik Jarczak, Kevin Roedl, Michael Sonntagbauer, Christian Putensen, Jens-Christian Schewe, Stefan F. Ehrentraut, Stefan Kreyer, Andreas Wehrfritz, Ixchel Castellanos, Karl Bihlmaier, Karsten Schmidt, Thorsten Brenner, Frank Herbstreit, Florian Espeter, Jan Wiefhoff, Richard K. Ellerkmann, Daniel Oswald, Björn Ellger, Gösta Lotz, Florian J. Raimann, Tobias Wengenmayer, Dawid L. Staudacher, Viviane Zotzmann, Onnen Moerer, Matthias Kochanek, Patricia Glaser, Falk Fichtner, Marc Bodenstein, Michael Findeisen, Vanessa Rembold, Markus Heim, Gerhard Schneider, Tobias Lahmer, Jan-Sören Padberg, Carsten Hullermann, Andre P. Becker, Carlos Metz, Peter Rosenberger, Valbona Mirakaj, Alice-Marie Bernard, Stephan Braune, Rebecca Roth, Anna Grau, Peter Heuschmann, Christian Karagiannidis

The history of substance abuse disorder in critically ill septic adolescent patients is associated with increased utilization of critical care resources and organ dysfunction

Ning Zhuo

A reassessment of the impact of substance use disorder on outcomes in adolescent sepsis

Xueneng Yang, Ruijuan Li

Management and monitoring strategies for severe cerebral malaria: a guide for the intensivist

Sonila Vathi, Alberto Corriero, Edith Elianna Rodríguez, Anthony Moreau, Elisa Gouvea Bogossian, Marta Baggiani, Maya Hites, Romain Sonneville, Fabio Silvio Taccone, Michele Salvagno

Correction: Transplant-free survival in acute liver failure patients receiving MARS®, plasma exchange or no liver support. A real-life 21-year retrospective cohort study in a referral center

Kieran Pinceaux, Félicie Bélicard, Valentin Coirier, Estelle Le Pabic, Pauline Guillot, Flora Delamaire, Benoît Painvin, Quentin Quelven, Mathieu Lesouhaitier, Adel Maamar, Arnaud Gacouin, Pauline Houssel-Debry, Karim Boudjema, Edouard Bardou-Jacquet, Jean-Marc Tadié, Florian Reizine, Christophe Camus

Where does the fluid go?

  • Open Access
  • Edema
  • Review

Robert G. Hahn

Carbon dioxide elimination as a guide to venoarterial extracorporeal membrane oxygenation weaning: a prospective observational study

  • Open Access
  • ECMO
  • Research

Yazhu Yang, Liangshan Wang, Chenglong Li, Hong Wang, Xin Hao, Yan Wang, Yiwen Wang, Ruike Lu, Xiaotong Hou, Zhongtao Du

Time-course changes in energy expenditure in sepsis: a prospective observational study

Weronika Wasyluk, Robert Fiut, Izabela Świetlicka, Magdalena Szukała, Agnieszka Zwolak, Joop Jonckheer, Wojciech Dąbrowski

Association between socio-economic status and outcomes among critically ill Covid-19 adult patients in France

Diane Naouri, Naïke Bigé, Tai Pham, Martin Dres, Gaëtan Béduneau, Alain Combes, Antoine Kimmoun, Alain Mercat, Albert Vuagnat, Matthieu Schmidt, Alexandre Demoule, Matthieu Jamme

Incidence and outcomes of extubation failure in mechanically ventilated patients with cirrhosis: a post-hoc analysis of a prospective multicenter study

Yassir Aarab, Joris Pensier, Fanny Garnier, Clement Monet, Ines Lakbar, Gerald Chanques, Audrey de Jong, Mathieu Capdevila, Samir Jaber

Comment on “immunosuppressive therapy management during sepsis in kidney transplant recipients: a prospective multicenter study”

Shuo Lin, Jianjie Ju, Zhouhua Wang

Outcomes of carbapenem-resistant Acinetobacter baumannii bloodstream infections in intensive care units and prognostic effect of different antimicrobial regimens

Chieh-Lung Chen, Kuang-Yao Yang, Chung-Kan Peng, Ming-Cheng Chan, Chau-Chyun Sheu, Jia-Yih Feng, Sheng-Huei Wang, Wei-Hsuan Huang, Chia-Min Chen, How-Yang Tseng, Yu-Chao Lin

Hemostatic abnormalities after trauma resuscitation: challenges and strategies in caring for the critically injured patient

Christopher R. Reed, Nicola Curry, Nicole P. Juffermans, Matthew D. Neal

Does obesity impact on weaning from invasive ventilation: a secondary analysis of the WEAN SAFE study

Alison Bell, Akira Kuriyama, Omid Khazaei, Bairbre A. McNicholas, Tài Pham, Leo Heunks, Giacomo Bellani, Laurent Brochard, Andrew J. Simpkin, John G. Laffey

Associations between long-term exposure to air pollutants and mortality risk of critically ill patients: a multi-center cohort study in central China

Lu Ye, Chen Li, Kun Qin, Liang Xu, Ping Jin, Zhanpeng Wang, Cong Zhang, Chun Yin, Yaolin Liu, Zhicheng Fang, Jingjun Lv, Peng Jia

Venous congestion and the geometry of Guyton

Jon-Emile S. Kenny, Per Werner Moller

Neuromuscular blockade and their monitoring in the intensive care unit: a multicenter observational prospective study

Bertrand Hermann, Guillaume Decormeille, Tiphanie Gobé, Nathanaël Mangeard, Adel Maamar, Saria Sayadi, Bénédicte Pernod, Nadine Robquin, Jean-Pierre Ponthus, Sophie Le Potier, Pierre Bouju, Angélique Balabanian, Antoine Frouin, Sébastien Moschietto, Gwenaelle Jacq, Emeline Villemont, Clémence Houbé, Anaïs Queyreau, Célina Morand, Florence Boissier, Jean-Baptiste Lascarrou, Sabine Valera, Sami Hraiech, Laure Clouet, Gaël Piton, Cindérella Noël, Anne Joosten, Cécilia Tabra Osorio, Adrien Constan, Jérôme Cecchini, Gwennaelle Mercier, Arnaud Bruyneel, Chloé Villamaux, François Pousset, Nicholas Heming, Laurent Poiroux, Jean-François Llitjos, Saber Davide Barbar

Do diabetes and poor control of acute stress-related hyperglycemia increase the risk of ICU-acquired infections? A retrospective assessment in patients with septic shock

Alice Friol, Clément Devautour, Anna Semenov, Juliette Pelle, Marie Renaudier, Sarah Benghanem, Alain Cariou, Jean-Paul Mira, Julien Charpentier, Frédéric Pène

Response to the Letter to the Editor: “Immunosuppressive therapy management during sepsis in kidney transplant recipients: a prospective multicenter study”

Valentin Rivet, Lara Zafrani

Development of a gene panel for immune status assessment in sepsis

Chao Gao, Xinxing Lu, Yiwei Jiang, Ying Tang, Yunhui Ni, Hanbing Chen, Xiaojing Wu, Xing Zhou, Yi Yang, Ling Liu, Jie Chao, Jianfeng Xie, Haibo Qiu

Distinct diurnal temperature rhythm patterns in critical illness myopathy: secondary analysis of two prospective trials

D. Mewes, S. Weber-Carstens, K. Rubarth, S. D. Boie, C. Spies, A. Kramer, J. Fielitz, T. Wollersheim, B. Ananthasubramaniam, F. Braune, L. Hancke, L. Spies, F. Balzer, L. J. Engelhardt

Impact of respiratory viruses detection on outcomes in ventilated nosocomial pneumonia: an exposed/unexposed study

Hermann Do Rego, Julien Dessajan, Quentin Le Hingrat, Laurence Armand Lefevre, Etienne De Montmollin, Michael Thy, Stéphane Ruckly, Romain Sonneville, Lila Bouadma, Nathalie Grall, Jean-François Timsit

Significance of positive semi-quantitative PCR tests on bronchoalveolar lavage for Pneumocystis jirovecii pneumonia in HIV-negative immunocompromised ICU patients with acute respiratory failure

Louis-Maxime Vaconsin, Christine Bonnal, Nicolas Argy, Julien Dessajan, Paul-Henri Wicky, Michael Thy, Etienne de Montmollin, Romain Sonneville, Lila Bouadma, Sandrine Houzé, Jean-François Timsit

The metabolic response to stress in critical illness: updated review on the pathophysiological mechanisms, consequences, and therapeutic implications

Raphael Mottale, Claire Dupuis, Sylwia Szklarzewska, Jean-Charles Preiser

Factors associated with ICU mortality and long-term outcomes in immunocompromised patients admitted to the intensive care unit for acute respiratory failure

  • Open Access
  • Research

Mélanie Métais, Jean-Pierre Frat, Stephan Ehrmann, Frédéric Pène, Maxens Decavèle, Nicolas Terzi, Gwenaël Prat, Maëlle Martin, Damien Contou, Arnaud Gacouin, Jeremy Bourenne, Christophe Girault, Christophe Vinsonneau, Jean Dellamonica, Guylaine Labro, Sébastien Jochmans, Alexandre Herbland, Jean-Pierre Quenot, Jérôme Devaquet, Dalila Benzekri, Stéphanie Ragot, Arnaud W. Thille, Rémi Coudroy, Emmanuel Vivier, Saad Nseir, Gwenhaël Colin, Didier Thevenin, Giacomo Grasselli, David Bougon, Mona Assefi, Claude Guérin, Thierry Lherm, Achille Kouatchet

Multimodal assessment of peripheral perfusion in critically ill patients: a pilot study

  • Open Access
  • Shock
  • Research

Zoé Demailly, Elena Modica, Eva Vitali, Francisco Sousa, Carlotta Dragoni, Irene Sbaraini Zernini, Claudio Annicchiarico, Charles Dehout, Fabienne Tamion, Emmanuel Besnier, Hassane Njimi, Elaine Cavalcante dos Santos, Fabio Silvio Taccone

ICU predictive factors of fibrotic changes following COVID-19 related ARDS: a RECOVIDS substudy

Matthieu Demeyere, Isabelle Fournel, Amadou-Khalilou Sow, Stéphanie Gélinotte, Martine Nyunga, Anissa Berraies, Marie Labruyère, Alexandre Ampere, Bertrand Sauneuf, Cédric Daubin, Agathe Delbove, Julio Badie, Pierre Bulpa, David Delacour, Clotilde Lefevre, Saad Nseir, Elise Artaud-Macari, Michel Ramakers, Vanessa Bironneau, Hugues Georges, Walid Oulehri, Arnaud-Felix Miailhe, Nicolas Delberghe, Béatrice La Combe, Elise Redureau, Caroline Clarot, Nicholas Sedillot, Thierry Dugernier, David Schnell, Laurie Lagache, Charlotte Salmon Gandonniere, Julien Maizel, Thierry Vanderlinden, Gaël Bourdin, Mélanie Adda, Gaëtan Plantefeve, Gaëtan Beduneau, Marjolaine Georges, Jean-Pierre Quenot, Pierre-Louis Declercq

Effects of fluids on sublingual microcirculation: a point of view review

  • Open Access
  • Shock
  • Review

Arnaldo Dubin

High-flow nasal cannula and intubation risk in severe PjP: methodological and clinical perspectives

Lulu Wang, Jinying Cheng

Physiological comparison of noninvasive ventilation and CPAP on inspiratory efforts after extubation in critically ill patients with morbid obesity: a post-hoc analysis

Martin Mahul, Mathieu Capdevila, Fabrice Galia, Audrey De Jong, Samir Jaber

Use of intravenous lipid emulsions in drug-induced toxicities: a 2025 narrative review

Gauthier Nendumba, Sydney Blackman, Nathan De Lissnyder, Marine Cillis, Patrick M. Honore

Response to “high-flow nasal cannula and intubation risk in severe PjP: methodological and clinical perspectives”

  • Open Access
  • Letter to the Editor

Florian Reizine, Vicky Stiegler, Benoit Tessoulin, Nahema Issa, Benjamin Gaborit, Francois Raffi, David Boutoille, Charlotte Biron, Maeva Lefebvre, Benjamin Jean Gaborit, Paul Le Turnier, Colin Deschanvres, Raphael Lecomte, Marie Chauveau, Romain Lécuyer, Antoine Asquier-Khati, Valentin Pineau, Marie Prime, Clarisse Delaunay, Hakim Essid, Vicky Steigler, Patrice Le Pape, Florent Morio, Rose-Anne Lavergne, Fakhri Jeddi, Stéphane Corvec, Pascale Bemer, Jocelyne Caillon, Aurélie Guillouzouic, Anne-Gaëlle Leroy, Karim Lakhal, Raphaël Cinotti, Antoine Roquilly, Mickael Vourc’h, Jean Reignier, Emmanuel Canet, Soraya Benguerfi, François Xavier Blanc, Cédric Bretonniere, Jean Morin, Camille Le Blanc, Hakim Alami, Fabrice Camou, Nahéma Issa, Olivier Guisset, Gaelle Mourissoux, Isabelle Accoceberry, Frederic Gabriel, Isabelle Accoceberry, Noémie Coron, Laurence Delhaes, Sébastien Imbert, Maxime Lefranc, Florian Lussac-Sorton, Amandine Rougeron, Marie Gousseff, Yoann Crabol, Grégory Corvaisier, Florent Lautredoux, Romain Lécuyer, Anne Cady, Myriam Auger, Pascal Pouedras

Re: “impact of aminoglycosides on survival rate and renal outcomes in patients with urosepsis: a multicenter retrospective study”

  • Open Access
  • Letter to the Editor

Min Li, Min Xu

Ultrasound indicators of organ venous congestion: a narrative review

  • Open Access
  • Review

Zouheir Ibrahim Bitar, Ossama Sajeh Maadarani, Mohamad Bitar

End-tidal carbon dioxide changes induced by passive leg raising can predict fluid responsiveness in patients on veno-arterial extracorporeal membrane oxygenation: a prospective, interventional study

  • Open Access
  • ECMO
  • Research

Timothée Hannequin, Aurore Ughetto, Jacob Eliet, Cinderella Blin, Aurélien Canon, Marine Saour, Philippe Gaudard, Celia Vidal, Nicolas Molinari, Pascal Colson, Marc Mourad

Further analysis and refinements of the perceived stressors in intensive care units (PS-ICU) scale: a French nation-wide cross-sectional multicentre study

  • Open Access
  • Research

Florent Lheureux, Maxime Jollivet, Juliette Chiron, Sarah Poulet, Alicia Fournier, Gilles Capellier, Laetitia Bodet-Contentin, Antoine Herault, Joffrey Hamam, Pascal Beuret, Pierre-Alexandre Lamizet, Mathieu Schoeffler, Bérengère Vivet, Christophe Guitton, Gaël Piton, Justine Perrot, Khaldoun Kuteifan, Céline Guichon, Hodane Yonis, Olivier Barbot, Carole Schwebel, Pierre-Yves Olivier, Enora Atchade, Alexis Dürr, Frédérique Schortgen, Claire Bourel, Diane Friedman, Caroline Hauw-Berlemont, Laura Federici, Anne-Sophie Muller, Kada Klouche, Charles Damoisel, Sabine Valera, Ghada Sboui, Cathy Lemaitre, Antonin Michaud, Alexandra Beurton, Emeline Buttazzoni, Camille Aïtout, Bérengère Araujo, Laurence Goncalves, Sylvie Canon, Anne Couvillers, Anne-Laure Poujol, Juliette Toulet, Belaïd Bouhemad, François Aptel, Cyril Goulenok, Alexandra Laurent, Maxime Granier, Clémentine Hoareau, Isabelle Bourgoin, Fabienne Tamion, Emilie Saint Leger, Déborah Hiron, Hubert Grand, Aude Londeix, Céline Marconnet, Florent Montini, Laetitia Volle, Karine Herbert, Corinne Mourioux, Laurence Groshenry, Claire Chagnat, Melissa Crotet, Juliette Meunier, Séverine Guillarme, Hadrien Winiszewski, Sarah Noir, Laure Clouet, Francis Augier, Isabelle Zamofing, Jean-Cyril Van Hamme, Marie-Anne Tisserand, Jean-Christophe Richard, Mathieu Rulliere, Emmanuelle Rouve, Florence Thevenot, Aurélie Maillach, Eve Merzouki, Carole Haubertin, Philippe Montravers, Aurélie Gouel-Cheron, Mathilde Dijoux, Martial Thyrault, Léopoldine Legrain, Cécilia Tabra Osorio, Emilie Aebischer, Raphaël Favory, Evelyne Egret, Djillali Annane, Anne Robin, Ségolène Jourdier, Sarah Ferte, Laurent Serpin, Cécile Capelli, Alice Preault, Delphine Daubin, Corinne Pelle, Claudine Gniadek, Stéphanie Galia, Jean-Marie Forel, Sabine Janowski, Jerôme Vandensteen, Julien Poissy, Vincent Castelain, Sylvie L’Hotellier, Jeanne Sovant, Muriel Fartoukh, Laurence Krzyzaniak, Pierre-Grégoire Guinot, Christelle Jault, Armand Mekontso Dessap, Maryline Couette, Sébastien Preau, Saadalla Nseir, Sandrine Ndinga Mondze, Mercedes Jourdain

Physiological and clinical significance of mean circulatory and mean systemic filling pressure

  • Open Access
  • Review

Sheldon Magder, Douglas Slobod, Antoine Vieillard-Baron

A predictive model for early intubation in patients with COVID–19–induced acute hypoxemic respiratory failure under awake prone position

Luis Morales–Quinteros, Nora Angélica Fuentes, Alfonso Muriel, Matías Olmos, Marina Busico, Alejandra Vitali, Adrián Gallardo, Erika P. Plata–Menchaca, Ricard Ferrer, Antonio Artigas, Mariano Esperatti

Bedside ventilatory settings guided by respiratory mechanics in acute respiratory distress syndrome

Davide Chiumello, Silvia Coppola, Pedro Leme Silva, Giulia Lais, Patricia R. M. Rocco, Lise Piquilloud

Spectrum, dose, and duration of antibiotic exposure and risk of intensive care unit–acquired carbapenem-resistant gram-negative bacteria: a prospective cohort study

Zhihui Chen, Jing Wu, Xiangru Ye, Zhonghua Li, JingWang, Yueru Tian, Lei Zhou, Jie Ni, Jialin Jin, Wenhong Zhang

Choosing wisely: comparing the carbon footprint of three respiratory sampling techniques for ventilator-associated pneumonia

Adam Celier, Charlotte Correard, Ines de Maisoncelle, Eric Dupont, Alexandre Demoule, Marie Lecronier

Applied physiology at the bedside: using invasive blood pressure as a true monitoring tool

  • Open Access
  • Review

Maxime Bertrand, Antoine Goury, Denis Chemla, Jean-Louis Teboul, Olfa Hamzaoui

Contact precautions prevent cross-contamination of extended-spectrum beta-lactamase-producing Enterobacterales in an intensive care unit: a prospective observational study

  • Open Access
  • Research

Nina Milerad, Christina Agvald Öhman, Inga Fröding, Christian G. Giske, Markus Castegren

Dec 24
Issue: 1/2024

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