Issue 5/2025
Content (34 Articles)
Expert Discussion on Immune Complex-Mediated Membranoproliferative Glomerulonephritis: Challenges and Considerations
- Open Access
- Glomerulonephritis
- Commentary
Richard A. Lafayette, Vivek Charu, Richard J. Glassock
Summary of Research: Efficacy of Trastuzumab Deruxtecan in HER2-Expressing Solid Tumors by Enrollment HER2 IHC Status: Post Hoc Analysis of DESTINY-PanTumor02
- Open Access
- Trastuzumab Deruxtecan
- Summary of Research
Ana Oaknin, Jung-Yun Lee, Vicky Makker, Do-Youn Oh, Susana Banerjee, Antonio González-Martín, Kyung Hae Jung, Iwona Ługowska, Luis Manso, Aránzazu Manzano, Bohuslav Melichar, Salvatore Siena, Daniil Stroyakovskiy, Anitra Fielding, Soham Puvvada, Ann Smith, Funda Meric-Bernstam
Efficacy and Safety of Recombinant Factor VIII in Previously Untreated and Previously Treated Children with Hemophilia A: A Systematic Review
- Open Access
- Hemophilia
- Review
Xiaoqin Feng, Xuan Zhou, Jing Sun, Zhenguo Wang
Comparative Effectiveness of mRNA-1273 and BNT162b2 COVID-19 Vaccines Among Adults with Underlying Medical Conditions: Systematic Literature Review and Pairwise Meta-Analysis Using GRADE
- Open Access
- SARS-CoV-2
- Review
Xuan Wang, Ankit Pahwa, Mary T. Bausch-Jurken, Anushri Chitkara, Pawana Sharma, Mia Malmenäs, Sonam Vats, Michael Gordon Whitfield, Kira Zhi Hua Lai, Priyadarsini Dasari, Ritu Gupta, Maria Nassim, Nicolas Van de Velde, Nathan Green, Ekkehard Beck
Targeting PACAP: Beyond Migraine to Cluster, Menstrual, and Post-traumatic Headaches
- Open Access
- Cluster Headache
- Review
Lanfranco Pellesi, Mona Ameri Chalmer, Song Guo, Thien Phu Do, Zheman Xiao, Paolo Martelletti
Prevention and Treatment of Intraoperative Complications During Gynecological Laparoscopic Surgery: Practical Tips and Tricks—A Narrative Review
- Open Access
- Operative Gynecology
- Review
Matteo Giorgi, Giorgia Schettini, Luca La banca, Alberto Cannoni, Alessandro Ginetti, Irene Colombi, Nassir Habib, Ramon Rovira, Francesco Martire, Lucia Lazzeri, Errico Zupi, Gabriele Centini
Management of Atherosclerotic Cardiovascular Risk in Inflammatory Bowel Disease: Current Perspectives
- Open Access
- Inflammatory Bowel Disease
- Review
Walter Masson, Gonzalo Fernández-Villar, Solange Martinez-Elhelou
A Randomised, Double-Blind Trial to Compare the Efficacy, Safety, and Immunogenicity of the Biosimilar Ustekinumab FYB202 with Reference Ustekinumab in Patients with Moderate-to-Severe Plaque Psoriasis
- Open Access
- Ustekinumab
- Original Research
Kim Papp, Sigrid Balser, Katrin Nopora, Piotr Rewerski, Brigitte Freudensprung, Michael Trieb
A Multicenter Single-Arm Study of Switching to Ferric Citrate Hydrate for Iron Deficiency Anemia in Patients Intolerant to Oral Iron: RIO-SWITCH
- Open Access
- Iron Deficiency Anemia
- Original Research
Osamu Wada-Hiraike, Aya Maruyama, Yuko Mitobe, Takayuki Iriyama, Mayuyo Mori-Uchino, Yutaka Osuga
Safety of iGlarLixi in Japanese People with Type 2 Diabetes: A Post-marketing Database Study
- Open Access
- Oral Antidiabetic Drugs
- Original Research
Hideaki Kaneto, Makiko Hatanaka, Yukiko Morimoto, Yoko Takahashi, Yasuo Terauchi
Burden of Comorbidities and Concomitant Medications and Their Associated Costs in Patients with Gastroenteropancreatic or Lung Neuroendocrine Tumors: Analysis of US Administrative Data
- Open Access
- Neuroendocrine Tumor
- Original Research
Jennifer A. Chan, Antonio Ribeiro-Oliveira Jr., Aude Houchard, Syvart Dennen, Yutong Liu, Sai Sriteja Boppudi Naga, Yajin Zhao, Christelle Pommie, Timon Vandamme, Jason Starr
Management of Oxidative Stress and Inflammation in Patients with Symptomatic Dry Eye Disease Treated with a Preservative-Free Ophthalmic Emulsion Combining Alpha-Lipoic Acid and High Molecular Weight Sodium Hyaluronate
- Xerophthalmia
- Original Research
Laure Chauchat, Camille Guerin, Marwan Sahyoun, Michel Guillon, Margarita Calonge
Falls and Fractures in Patients with Geographic Atrophy: A US Claims Data Analysis
- Open Access
- Macular Degeneration
- Original Research
Allen Hu, Rachel E. Teneralli, Rachelle Rodriguez, Alyshah Abdul Sultan, Colleen Garey, Jessica Ackert, Rose Ong
First-Line Tislelizumab Plus Chemotherapy for Advanced Gastric Cancer with Programmed Death-Ligand 1 Expression ≥ 1%: A Retrospective Analysis of RATIONALE-305
- Open Access
- Gastric Cancer
- Original Research
Markus Moehler, Do-Youn Oh, Ken Kato, Tobias Arkenau, Josep Tabernero, Keun-Wook Lee, Sun Young Rha, Hidekazu Hirano, David Spigel, Kensei Yamaguchi, Lucjan Wyrwicz, Umut Disel, Roberto A. Pazo-Cid, Lorenzo Fornaro, Yaling Xu, Tao Sheng, Silu Yang, Alysha Kadva, Marcia Cruz-Correa, Rui-Hua Xu
First-Line Tislelizumab Plus Chemotherapy for Esophageal Squamous Cell Carcinoma with Programmed Death-Ligand 1 Expression ≥ 1%: A Retrospective Analysis of RATIONALE-306
- Open Access
- Cytostatic Therapy
- Original Research
Jianming Xu, Ken Kato, Richard Hubner, Sook Ryun Park, Takashi Kojima, Ryu Ishihara, Lucjan Wyrwicz, Eric Van Cutsem, Paula Jimenez-Fonseca, Hongqian Wu, Lei Wang, Sebastian Yan, Jingwen Shi, Alysha Kadva, Harry H. Yoon
Pharmacokinetic, Pharmacokinetic/Pharmacodynamic, and Safety Investigations of Cefiderocol in Chinese Healthy Subjects
- Open Access
- Pharmacokinetics
- Original Research
Chuhan Zhang, Shuyan Yu, Size Li, Xiaojie Wu, Qiong Wei, Jinjie He, Guoying Cao, Haijing Yang, Jingjing Wang, Kohei Fujitani, Takayuki Katsube, Jing Zhang, Honghong Dou
Single-Tablet Combination Therapy of Macitentan/Tadalafil for Patients with Pulmonary Arterial Hypertension: Qualitative Interview Study of the A DUE Phase 3 Trial
- Open Access
- Arterial Hypertension
- Original Research
Fenling Fan, Stacy Davis, Claire Burbridge, Kelly Chin, Michael Friberg, Ekkehard Grünig, Melanie Hughes, Pavel Jansa, Jörg Linder, Jennifer Rafalski, Alvaro Agustin Rodriguez, Jason A. Randall
A Noninterventional, Cross-Sectional Study to Assess Patient Prostate Cancer Treatment Preferences and Experiences in Europe
- Open Access
- Prostate Cancer
- Original Research
Emmanuelle Kaltenbach, Ana Maria Rodriguez-Leboeuf, Patrick Cabri, Mickael Henry-Szatkowski, Mehmet Inceer, Emma Karim, Valérie Perrot, Giuseppe Fallara, Matteo Ferro
A Real-World Study on the Use, Effectiveness, and Safety of Esketamine Nasal Spray in Patients with Treatment-Resistant Depression: INTEGRATE Study
- Esketamine
- Original Research
Patricio Molero, Angela Ibañez, Javier de Diego-Adeliño, J. Antoni Ramos-Quiroga, Marta García Dorado, Paola M. López Rengel, Pilar A. Saiz
An Up-to-Date Description of the Use of Non-steroidal Anti-inflammatory Drugs (NSAIDs) in Italy: Evidence from Real Clinical Practice
- Open Access
- Etoricoxib
- Original Research
Valentina Perrone, Chiara Veronesi, Maria Ciappetta, Domenico Lucatelli, Andrea Cinti Luciani, Luca Degli Esposti
Pharmacokinetic Comparability and Safety Between Original and Citrate-Free Mirikizumab Formulations for Subcutaneous Injections: Results from Three Clinical Trials
- Open Access
- Ulcerative Colitis
- Original Research
Yuki Otani, Brian G. Feagan, Geert R. D’Haens, Rodrigo Escobar, Nathan J. Morris, Christopher D. Payne, Michelle Ugolini Lopes, Xin Zhang
Point of Care Nucleic Acid Testing for Influenza-Like Illness: A Cost–Consequence Analysis for High-Risk Patients in Primary Care in Germany
- Open Access
- Influenza
- Original Research
Johannes Pöhlmann, Anika Joecker, Tanja Wittki, Tray Brown, Richard F. Pollock, Jordan Chase
Real-World Evidence for Baricitinib in the Treatment of Rheumatoid Arthritis in Spain: A Systematic Literature Review
- Open Access
- Baricitinib
- Original Research
José Rosas, Joaquín Belzunegui, Blanca Hernández-Cruz, Itxaso Aguirregabiria, Sebastián Moyano, Amelia Cobo, Silvia Díaz-Cerezo
Mobility and Quality of Life in Adults with Paediatric-Onset Hypophosphatasia Treated with Asfotase Alfa: Results from UK Managed Access Agreement
- Open Access
- Hypophosphatasia
- Original Research
Katie E. Moss, Richard Keen, Shona Fang, Alexandros Zygouras, Muhammad K. Javaid, Tarekegn Geberhiwot, Kenneth E. S. Poole, Peter Selby, Jennifer S. Walsh, Judith S. Bubbear
Loncastuximab Tesirine Versus Polatuzumab Vedotin Plus Bendamustine and Rituximab in Relapsed/Refractory DLBCL After ≥ 2 Lines of Therapy: Matching-Adjusted Indirect Comparison
- Open Access
- Diffuse Large B-Cell Lymphoma
- Original Research
Koo Wilson, Francesca Chiodi, Abby Paine, Zalmai Hakimi, Victoria Ward, Tom Macmillan, Daniel Eriksson, Silvia Mappa
Evinacumab for Homozygous Familial Hypercholesterolemia: The Italian Cohort of the ELIPSE HoFH Study
- Open Access
- Original Research
Gabriella Iannuzzo, Ilenia Calcaterra, Marco Gentile, Claudia Stanzione, Francesca De Ruberto, Maria Donata Di Taranto, Giuliana Fortunato, Matteo Di Minno
Pembrolizumab in Patients of Chinese Descent with Microsatellite Instability-high/Mismatch Repair Deficient Advanced Solid Tumors: KEYNOTE-158 Final Analysis
- Solid Tumor
- Brief Report
Xiaohua Wu, Yimin Mao, Nong Xu, Yuxian Bai, Dong Wang, Xiaojun Chen, Xianli Yin, Yanhong Deng, Jianwei Yang, Jieqing Zhang, Jie Tang, Yi Huang, Jiayi Li, Suxia Luo, Hong Zheng, Weidong Zhao, Miaomiao Xu, Nan Li, Yixiang Mao, Alexander Gozman, Jianming Xu
Impact of Different Definitions of Vaso-Occlusion on Efficacy Assessments in Sickle Cell Disease Clinical Trials
- Open Access
- Priapism
- Brief Report
Haydar Frangoul, Franco Locatelli, Michael J. Eckrich, Suzan Imren, Nanxin Li, Fengjuan Xuan, Stephan A. Grupp
Healthcare Utilization and Costs of Care in Patients With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation After Initiating Oral Therapies: Real-World Analysis in the US Medicare Population
- Open Access
- Lubiprostone
- Brief Report
Eric Shah, Tsung-Ying Lee, Zachary Baldwin, Jens Kort, Masakazu Ando, Steven W. Champaloux, Mena Boules, Yuri Sanchez Gonzalez
The Composite Number Needed to Treat for Semaglutide in Populations with Overweight or Obesity and Established Cardiovascular Disease Without Diabetes
- Open Access
- Semaglutide
- Brief Report
Christopher Lübker, Jigish Bhavsar, Ruben Duque do Vale, Scott S. Emerson, Emil Nørtoft, Jorge Plutzky, Geraint Roberts, Jens Magelund Tarp, A. Michael Lincoff
Fertility Outcomes in Risdiplam-Treated Male Patients with Spinal Muscular Atrophy: A Multicenter Case Series
- Open Access
- Spinal Muscular Atrophy
- Case Series
Shelley Coskery, Marcus Erdler, Margaret R. Frey, Michael A. Lopez
Letter to the Editor Regarding “Predicting Asthma Exacerbations Using Machine Learning Models”
- Open Access
- Bronchial Asthma
- Letter
Zekai Yu
A Response to: Letter to the Editor Regarding “Efficacy of Cooled-Radiofrequency Ablation of the Genicular Nerve as Treatment for Chronic Knee Pain: A Retrospective Study”
- Open Access
- Osteoarthrosis
- Letter
Alaa Abd-Elsayed, Andrew Matta
