Issue 2/2025
Content (40 Articles)
Addressing the Human Experience of Chronic Kidney Disease: A Call to Transform Kidney Care
- Open Access
- Chronic Kidney Disease
- Commentary
Ricardo Correa-Rotter, Steven J. Chadban, Laura Christen, Kelli Collins Damron, Lweendo Hamusankwa, Sarah Jarvis, Surendra Pentakota, Marisol Robles, Petrina Stevens, Christoph Wanner
An Access-Focused Patient-Centric Value Assessment Framework for Medication Formulary Decision-Making in Immune-Mediated Inflammatory Diseases
- Open Access
- Commentary
Min Yang, Manish Mittal, A. Mark Fendrick, Diana Brixner, Bruce W. Sherman, Yifei Liu, Pankaj Patel, Jerry Clewell, Qing Liu, Louis P. Garrison Jr.
Influence of Treatment Effect Modifiers in Fabry Disease: A Systematic Literature Review
- Open Access
- Fabry Disease
- Review
Khashayar Azimpour, Carla Tordoff-Gibson, Patricia Dorling, Irene Koulinska, Swati Kunduri, Victor Laliman-Khara, Anna Forsythe
Effects of Current Therapies on Disease Progression in Fabry Disease: A Narrative Review for Better Patient Management in Clinical Practice
- Open Access
- Fabry Disease
- Review
Renzo Mignani, Elena Biagini, Vittoria Cianci, Federico Pieruzzi, Antonio Pisani, Antonino Tuttolomondo, Maurizio Pieroni
Machine Learning Applications in Acute Coronary Syndrome: Diagnosis, Outcomes and Management
- Acute Coronary Syndrome
- Review
Shanshan Nie, Shan Zhang, Yuhang Zhao, Xun Li, Huaming Xu, Yongxia Wang, Xinlu Wang, Mingjun Zhu
Is COVID-19 Still a Threat? An Expert Opinion Review on the Continued Healthcare Burden in Immunocompromised Individuals
- Open Access
- COVID-19
- Review
Christoph D. Spinner, Samira Bell, Hermann Einsele, Cécile Tremblay, Michel Goldman, Zain Chagla, Axel Finckh, Christopher J. Edwards, Igor Aurer, Odile Launay, Carolina Casañas i Comabella, Samantha James, Sabada Dube, Katarzyna Borkowska, Fungwe Jah, Walid Kandeil, Renata T. C. Yokota, Cécile Artaud, Jacques-Eric Gottenberg, Loreto Gesualdo, Dominique Bertrand, Sofie Arnetorp, Gkikas Magiorkinis
One-Year Insights into the GLOBOSTAD Multinational Prospective Observational Study of Patients Receiving Dupilumab for Atopic Dermatitis
- Open Access
- Dupilumab
- Original Research
Piergiacomo Calzavara-Pinton, Chia-Yu Chu, Hilde Lapeere, Mariateresa Rossi, Silvia M. Ferrucci, Wen-Hung Chung, Anne-Claire Fougerousse, Daria S. Fomina, Gregor Holzer, Jarmila Čelakovská, Mona Al-Ahmad, Thrasyvoulos Tzellos, Jiangming Wu, Marius Ardeleanu, Kwinten Bosman
Comparison of On-Label Treatment Persistence in Real-World Patients with Psoriatic Arthritis Receiving Guselkumab Versus Subcutaneous Interleukin-17A Inhibitors
- Open Access
- Guselkumab
- Original Research
Philip J. Mease, Shannon A. Ferrante, Natalie J. Shiff, Timothy P. Fitzgerald, Soumya D. Chakravarty, Jessica A. Walsh
Genetic Etiologies and Outcomes in Malignancy and Mortality in Activated Phosphoinositide 3-Kinase Delta Syndrome: A Systematic Review
- Open Access
- Lymphoma
- Original Research
Katharina Büsch, Heidi L. Memmott, Heather M. McLaughlin, Julia E. M. Upton, Amanda Harrington
A Pharmacoeconomic Study of Post-Exposure Prophylaxis Strategies for Influenza Virus Infections in Japan
- Oseltamivir
- Original Research
Naoto Nakagawa, Runa Ono, Keita Odanaka, Hiroshi Ohara, Shigeki Kisara, Kitae Ito
Glucagon-Like Peptide-1 Receptor Agonist-Experienced Adults with Type 2 Diabetes Switching to Once-Weekly Semaglutide in a Real-World Setting: SURE Program Post Hoc Analysis
- Open Access
- Semaglutide
- Original Research
Gottfried Rudofsky, Markus Menzen, Louis Potier, Andrei-Mircea Catarig, Alice Clark, Prachi Priyadarshini, Cristina Abreu
Efficacy of Dapagliflozin + Sitagliptin + Metformin Versus Sitagliptin + Metformin in T2DM Inadequately Controlled on Metformin Monotherapy: A Multicentric Randomized Trial
- Open Access
- Sitagliptin
- Original Research
Awadhesh Kumar Singh, Ashok Kumar Das, L. Sreenivasa Murthy, Samit Ghosal, Rakesh Sahay, K. V. S. Harikumar, Ganesh Hosahithlu Keshava, Mayur Agarwal, G. Vijayakumar, Pramila Kalra, Piyush Lodha, Sambit Das, Shehla Shaikh, Soumik Goswami, T. P. Ajish, Prashant Kumthekar, Mihir Upadhyay, Anthuvan Thamburaj, Aushili Mahule, Ashish Prasad, Abhijit Pednekar
Pharmacokinetics, Pharmacodynamics, Bioavailability, and Immunogenicity of Obexelimab Following Subcutaneous Administration in Healthy Japanese and Non-Japanese Volunteers
- Pharmacokinetics
- Original Research
Xiaodong Wang, Rachel Kirk, Mark Matijevic, Minggeng Gao, Allen Poma, Shauna Quinn, Sujata Arora, Tanya Fischer
Adherence and Persistence with Single-Inhaler Triple Therapy Among Patients with COPD Using Commercial and Medicare Advantage US Health Plan Claims Data
- Open Access
- Chronic Obstructive Lung Disease
- Original Research
Corinne Young, Lydia Y. Lee, Kristi K. DiRocco, Guillaume Germain, Jacob Klimek, François Laliberté, Dominique Lejeune, Stephen G. Noorduyn, Rosirene Paczkowski
Baseline Characteristics of Dupilumab-Treated Patients with Asthma in the Real World: The RAPID Global Registry
- Open Access
- Bronchial Asthma
- Original Research
Njira L. Lugogo, Xavier Soler, Yasuhiro Gon, Andréanne Côté, Ole Hilberg, Changming Xia, Yi Zhang, Lucía de Prado Gómez, Paul J. Rowe, Amr Radwan, Juby A. Jacob-Nara, Yamo Deniz, Anju T. Peters
Qualitative Assessment of Health-Related Quality of Life Impacts Associated with Sickle Cell Disease in the United States and United Kingdom
- Open Access
- Fatigue
- Original Research
Jennifer Drahos, Adriana Boateng-Kuffour, Melanie Calvert, Ashley Valentine, Anthony Mason, Nanxin Li, Zahra Pakbaz, Farrukh Shah, Antony P. Martin
Correlation Between Disease-Free Survival Endpoints and Overall Survival in Elderly Patients with Early-Stage HER2-Negative Breast Cancer: A SEER-Medicare Analysis
- Open Access
- Breast Cancer
- Original Research
Jagadeswara R. Earla, Allison W. Kurian, Kalé Kponee-Shovein, Malena Mahendran, Yan Song, Qi Hua, Annalise Hilts, Yezhou Sun, Kim M. Hirshfield, Mark Robson, Jaime A. Mejia
Long-Term Clinical and Economic Effects of Switching to Once-Weekly Semaglutide from Other GLP-1 RAs Among Patients with Type 2 Diabetes in China: A Modeling Projection Study
- Semaglutide
- Original Research
Ying Hu, Xianwen Chen, Huimin Zou, Hao Zhang, Qi Ni, Yijun Li, Carolina Oi Lam Ung, Hao Hu, Yiming Mu
Healthcare Utilization, Costs, and Treatment Discontinuation in Adults with Episodic Migraine Initiating Galcanezumab Versus Rimegepant: A US Retrospective Claims Analysis
- Open Access
- Galcanezumab
- Original Research
Gilwan Kim, Margaret Hoyt, Armen Zakharyan, Jennifer Durica, Alexandra Wallem, Lars Viktrup
Content Validation of the QOL-B-RD and PROMIS-F SF-7a to Measure Respiratory and Fatigue Symptoms of MAC Lung Disease
- Open Access
- Fatigue
- Original Research
Kelly P. McCarrier, Mariam Hassan, Dayton W. Yuen, Jui-Hua Tsai, Nancy Touba, Kevin C. Mange
An Indirect Treatment Comparison of Lenvatinib for the First-Line Treatment of Patients with Unresectable Hepatocellular Carcinoma
- Open Access
- Lenvatinib
- Original Research
Kerigo Ndirangu, Abby Paine, Hollie Pilkington, David Trueman
Cost-Effectiveness Analysis of Finerenone for Treatment of Chronic Kidney Disease in Patients with Type 2 Diabetes from Japanese Payer Perspective
- Open Access
- Finerenone
- Original Research
Ataru Igarashi, Kenichi Ohara, Hiroyuki Matsuda, Junko Morii, Suchitra Jagannathan, Ronald Filomeno
Population Pharmacokinetics of Trofinetide in a Pediatric Population Aged 2–4 Years with Rett Syndrome
- Open Access
- Rett Syndrome
- Original Research
Mona Darwish, Julie Passarell, Kelly Maxwell, Heather Bradley, Kathie M. Bishop, James M. Youakim
Population Pharmacokinetic Modeling to Support Trofinetide Dosing for the Treatment of Rett Syndrome
- Open Access
- Rett Syndrome
- Original Research
Mona Darwish, Julie Passarell, Kelly Maxwell, James M. Youakim, Heather Bradley, Kathie M. Bishop
The Urgency Numeric Rating Scale: Psychometric Evaluation in Adults with Crohn’s Disease
- Open Access
- Crohn's Disease
- Original Research
Marla Dubinsky, Aisha Vadhariya, Sylvia Su, Xian Zhou, Frederick Durand, Claudine Clucas, Larissa Stassek, Ariane K. Kawata, Simon Travis
Medicare Advantage Population in the United States: Outcomes of Patients with Asthma Treated with ICS/LABA Before and After Initiation with Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI)
- Open Access
- Bronchial Asthma
- Original Research
Alan P. Baptist, Guillaume Germain, Jacob Klimek, François Laliberté, Robert C. Schell, Sergio Forero-Schwanhaeuser, Alison Moore, Stephen G. Noorduyn, Rosirene Paczkowski
Real-World Safety, Tolerability and Effectiveness of Nintedanib in Patients with Idiopathic Pulmonary Fibrosis: Final Report of Post-marketing Surveillance in Japan
- Open Access
- Nintedanib
- Original Research
Yoshikazu Inoue, Takashi Ogura, Arata Azuma, Yasuhiro Kondoh, Sakae Homma, Kenya Muraishi, Rie Ikeda, Kaori Ochiai, Yukihiko Sugiyama, Toshihiro Nukiwa
Clinical Features and Current Pharmacotherapy of OAB in Practice: Ideal and Reality
- Open Access
- Overactive Bladder
- Original Research
Kazuna Tsubouchi, Hisatomi Arima, Taiki Emoto, Hiroshi Nakazawa, Takahiro Kitano, Masashi Mikami, Chikao Aoyagi, Hiroshi Matsuzaki, Kosuke Tominaga, Naotaka Gunge, Takeshi Miyazaki, Yu Okabe, Nobuyuki Nakamura, Yuichiro Fukuhara, Masahiro Tachibana, Chizuru Nakagawa, Fumihiro Yamazaki, Nobuhiro Haga
Simplified Approach to Managing Newly Diagnosed Patients with Mild-to-Moderate Hypertension in Routine Clinical Practice
- Open Access
- Perindopril
- Original Research
Stella S. Daskalopoulou, Helena Papacostas-Quintanilla, Romualda Brzozowska-Villatte
Comparative Effectiveness of Fluticasone Furoate/Umeclidinium/Vilanterol and Budesonide/Glycopyrrolate/Formoterol Fumarate among US Patients with Chronic Obstructive Pulmonary Disease
- Open Access
- COPD Exacerbation
- Original Research
David Mannino, Stephen Weng, Guillaume Germain, Julien Boudreau, Anabelle Tardif-Samson, Sergio Forero-Schwanhaeuser, François Laliberté, Patrick Gravelle, Chris H. Compton, Stephen G. Noorduyn, Rosirene Paczkowski
Safety of Fezolinetant for Treatment of Moderate to Severe Vasomotor Symptoms Due to Menopause: Pooled Analysis of Three Randomized Phase 3 Studies
- Open Access
- Menopause
- Original Research
Risa Kagan, Antonio Cano, Rossella E. Nappi, Marci L. English, Shayna Mancuso, Xi Wu, Faith D. Ottery
Understanding MASH: An Examination of Progression and Clinical Outcomes by Disease Severity in the TARGET-NASH Database
- Open Access
- Metabolic Dysfunction-Associated Steatohepatitis
- Original Research
Rakesh Luthra, Aarth Sheth
Costs of Oral Corticosteroid Use in Patients with Severe Asthma With/Without Chronic Rhinosinusitis with Nasal Polyps: Data from the Italian SANI Registry
- Open Access
- Bronchial Asthma
- Original Research
Enrico Heffler, Francesco Blasi, Pierluigi Paggiaro, Giorgio Walter Canonica
US Real-World Effectiveness, Tolerability, and Healthcare Resource Utilization After Addition of Fremanezumab for Preventive Treatment in Patients Using Gepants for Acute Treatment of Migraine: Results From a Retrospective Chart Review
- Open Access
- Fremanezumab
- Original Research
Patrick Eugeni, Megan E. Rooney, Nicolas P. Saikali, Zhongzheng Niu, Maurice T. Driessen, Lynda J. Krasenbaum, Karen Carr, Michael J. Seminerio, Jennifer W. McVige
Trifluridine/Tipiracil (FTD/TPI) in Metastatic Colorectal Cancer in Hong Kong: A Territory-Wide Cohort Study
- Open Access
- Neutropenia
- Original Research
Ka-On Lam, Karen Hoi-Lam Li, Roland Ching-Yu Leung, Vikki Tang, Thomas Yau
Randomised, Placebo-Controlled, Double-Blind Trial to Assess Efficacy and Safety of ELOM-080 in Outpatients with COVID-19
- Open Access
- COVID-19
- Original Research
Michael Dreher, Hanna-Teresa Heier, Andrea Kienle-Gogolok, Kristina Röschmann-Doose, Jörg Simon, Ravi Singhal, Heidrun Täschner, Jörn Thomsen, Joachim Weimer, Thomas Wittig, Otto Wonhas, Manuela Thinesse-Mallwitz
Real-World Effectiveness of Long-Acting Injectable and Oral Antipsychotic Agents in US Medicare Patients with Schizophrenia
- Open Access
- Risperidone
- Original Research
Pengxiang Li, Zhi Geng, Carmela Benson, Charmi Patel, Jalpa A. Doshi
Assessment of the Potential Clinical and Economic Impact of Weight Loss in the Adult Population with Obesity and Associated Comorbidities in Spain
- Open Access
- Obesity
- Original Research
María Dolores Ballesteros-Pomar, Ened Rodríguez-Urgellés, Miquel Sastre-Belío, Alberto Martín-Lorenzo, Volker Schnecke, Lluís Segú, Max Brosa, Nuria Vilarrasa
CKD-Associated Pruritus is Associated with Greater Use of Antidepressants and Anti-pruritus Medications
- Open Access
- Pruritus
- Brief Report
Jasmine Ion Titapiccolo, Luca Neri, Thilo Schaufler, Hans-Jurgen Arens, Len Usvyat, Stefano Stuard, Marco Soro
Correction to: Oleogel-S10 in Dystrophic Epidermolysis Bullosa: A Case Series Evaluating the Impact on Wound Burden Over Two Years
- Open Access
- Epidermolysis Bullosa
- Correction
Mauricio Torres Pradilla, Erick Álvarez, Mónica Novoa, Ivonne Lozano, Maribel Trujillo
