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Open Access 01-11-2024 | Acne Inversa | ORIGINAL PAPER

Hidradenitis suppurativa and female infertility: a pilot study conducted amongst 110 dermatological patients

Authors: Cecilia Egede Medianfar, Christoffer Kursawe Larsen, Sara Karoline Saunte, Ditte Marie Louise Saunte, Gregor Borut Ernst Jemec, Rune Kjærsgaard Andersen

Published in: Archives of Dermatological Research | Issue 9/2024

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Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with severe consequences on quality of life. One aspect of this is that HS has been linked to an increased risk of infertility, but as data is still limited, it is not known if the association reflects causality. We performed a cross-sectional study of 161 female participants included at Zealand University Hospital, Roskilde, Denmark. Data regarding basic demographics, infertility, pregnancies, sexual function, and known factors with impact on fertility was collected. Logistic regressions were performed to analyze the association between HS and infertility, adjusting for factors that influence fertility. The study population consisted of 55 patients with HS, 55 patients with other dermatological diseases (ODD), and 51 healthy controls (HC). The HS group had a higher BMI, lower sexual function, and a higher tobacco use. We found no significant difference between the three groups in terms of whether they had children, the number of children they had, infertility, or whether they had received fertility treatments. The logistic analyses found no correlation between HS and infertility, and adjusting for factors affecting infertility did not alter this result. This study did not find a significant difference in infertility between patients with HS compared to those with ODD or HC. This result was not affected by adjustments for other factors known to influence fertility. Interestingly, the lower sexual function in the HS group did not appear to influence their desire or ability to conceive.
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Metadata
Title
Hidradenitis suppurativa and female infertility: a pilot study conducted amongst 110 dermatological patients
Authors
Cecilia Egede Medianfar
Christoffer Kursawe Larsen
Sara Karoline Saunte
Ditte Marie Louise Saunte
Gregor Borut Ernst Jemec
Rune Kjærsgaard Andersen
Publication date
01-11-2024
Publisher
Springer Berlin Heidelberg
Published in
Archives of Dermatological Research / Issue 9/2024
Print ISSN: 0340-3696
Electronic ISSN: 1432-069X
DOI
https://doi.org/10.1007/s00403-024-03390-6

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