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12-03-2025 | Breast Radiology

Accuracy of abbreviated magnetic resonance compared to 3-dimensional mammography and ultrasound in early detection of breast cancer

Authors: Sara El Garwany, Azza Abdel-hamid Gad, Sahar Mahmoud Mansour, Mohammad Ahmed Al-Shatouri, Taghreed Alshafeiy, Ahmed Fathy AlSerafi

Published in: La radiologia medica

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Abstract

Background

The purpose of this study is to assess the usefulness of the novel abbreviated MR (AB-MR) protocol in the screening of women with an intermediate risk of breast cancer. Sixty women with a Tyrer–Cuzick model-determined intermediate risk of breast cancer underwent AB-MR, mammography, and tomosynthesis examinations; as an auxiliary procedure, ultrasound imaging was carried out. Every modality was allocated a final BI-RADS category. Time spent on acquisition and interpretation was also noted. Pathological confirmation was obtained in all cases exhibiting malignant findings. The difference in sensitivity and specificity between the two modalities was evaluated using McNemar's test.

Results

When compared to traditional screening methods, AB-MR demonstrated 100% NPV, 98% specificity, 66.7% PPV, and 100% sensitivity in women with intermediate risk of breast cancer. Comparing mammography/ultrasound to positive malignancies verified by biopsy, the results indicated 100% sensitivity, 96.5% specificity, 60% PPV, and 100% NPV. Complete agreement was observed between abbreviated MR and malignant biopsies (100% sensitivity, specificity, NPV, and PPV). For AB-MR and mammography, the average reading time was 4 min and 5 min, respectively. The average acquisition time for AB-MRI was around 10 min, whereas the average time for complete MR imaging is 17 min.

Conclusion

AB-MR has better sensitivity, specificity, PPV, and NPV in screening of intermediate- and high-risk breast cancer. Acquisition time was shorter than full MR protocol. Reading time was decreased in respect of mammography. MRI screening ought to be more practical with the AB-MR protocol.
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Metadata
Title
Accuracy of abbreviated magnetic resonance compared to 3-dimensional mammography and ultrasound in early detection of breast cancer
Authors
Sara El Garwany
Azza Abdel-hamid Gad
Sahar Mahmoud Mansour
Mohammad Ahmed Al-Shatouri
Taghreed Alshafeiy
Ahmed Fathy AlSerafi
Publication date
12-03-2025
Publisher
Springer Milan
Published in
La radiologia medica
Print ISSN: 0033-8362
Electronic ISSN: 1826-6983
DOI
https://doi.org/10.1007/s11547-025-01983-3